Andrew VanDemark

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University of Pittsburgh

United States

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Recent Grants

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Structure of GDAP1 bound to a product of lipid peroxidation

Open Date: 2023-03-01

Close Date: 2025-02-28

Grant: Close

Discovery of Cell-based Chemical Probes Targeting Aberrant Angiogenesis in the Eye

Open Date: 2022-05-01

Close Date: 2024-04-30

Articles (9)

Year:

2023

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2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

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UNITED STATES

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Oleksandr Kapralov

University of Pittsburgh

UNITED STATES

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Karolina Mikulska-Ruminska

Assistant Professor

Nicolaus Copernicus University

POLAND

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Michael J. Palladino

University of Pittsburgh

UNITED STATES

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Yulia Tyurina

University of Pittsburgh

UNITED STATES

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Ahmad Cluntun

Assistant Professor

Rutgers University

UNITED STATES

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Andrew VanDemark

Research Interests

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Recent Grants

Articles (9)

Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Itavastatin and Resveratrol increase triosephosphate isomerase protein (TPI) in a newly identified variant, TPIQ181P, that confers TPI deficiency.

Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death.

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells

Structural and functional divergence of GDAP1 from the glutathione S‐transferase superfamily

Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily

Collaborators (10)

Dean Tolan

Svetlana N Samovich

Haider H. Dar

Heidi Schubert

Qin Yang

Oleksandr Kapralov

Karolina Mikulska-Ruminska

Michael J. Palladino

Yulia Tyurina

Ahmad Cluntun

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