Karolina Mikulska-Ruminska

Has grant

Assistant Professor

Nicolaus Copernicus University

Poland

Research Interests

Explore related searches

Professors in Poland

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Karolina Mikulska-Ruminska is an Assistant Professor at Nicolaus Copernicus University in Poland. Her research focuses on enzyme dynamics and interactions, specifically in the context of lipoxygenases and ferroptosis. Recent articles include investigations into protein tunnels, interactions, and the role of polyunsaturated fatty acids in cell death processes.

Recent Grants

Grant: Close

Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell death

Open Date: 2020-07-01

Close Date: 2023-07-01

Grant: Close

nanoALPS – NanoIR Autism Linked Proteins Studies

Open Date: 2013-09-01

Close Date: 2014-02-01

Grant: Close

Mechanics of single molecules: REELIN - neuronal growth steering protein

Open Date: 2013-02-01

Close Date: 2016-02-01

Grant: Close

Nanomechanics of neuronal cell adhesion molecules - studies with steered molecular dynamics and single molecule force spectroscopy

Open Date: 2012-10-01

Close Date: 2013-10-01

Articles (18)

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (11)

Wieslaw Nowak

Head, Professor

Nicolaus Copernicus University

POLAND

View details

Vladimir Tyurin

University of Pittsburgh

UNITED STATES

View details

Svetlana N Samovich

Assistant Professor

Columbia University

UNITED STATES

View details

Valerian E. Kagan

Professor

University of Pittsburgh

UNITED STATES

View details

Andrew VanDemark

University of Pittsburgh

UNITED STATES

View details

Haider H. Dar

University of Pittsburgh

UNITED STATES

View details

Bruno Lapied

Professor in Neurophysiology

Université d'Angers

FRANCE

View details

Qin Yang

University of Pittsburgh

UNITED STATES

View details

Oleksandr Kapralov

University of Pittsburgh

UNITED STATES

View details

Yulia Tyurina

University of Pittsburgh

UNITED STATES

View details

Andrew Amoscato

University of Pittsburgh

UNITED STATES

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Karolina Mikulska-Ruminska

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (18)

The presence of substrate warrants oxygen access tunnels toward the catalytic site of lipoxygenases

BPS2025 - CaviTracer: A ProDy tool for mapping protein tunnels and channels with application in lipoxygenases

InSty: A ProDy Module for Evaluating Protein Interactions and Stability

Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.

A New Function of PUFA-Plasmalogens in Ferroptosis

<i>WatFinder</i>: a <i>ProDy</i> tool for protein–water interactions

Prody's latest advancements: Gaining insights into protein-protein and protein-water interactions, and their role in protein dynamics

Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis.

Membrane regulation of 15LOX-1/PEBP1 complex prompts the generation of ferroptotic signals, oxygenated PEs

Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

NO<sup>●</sup> Represses the Oxygenation of Arachidonoyl PE by 15LOX/PEBP1: Mechanism and Role in Ferroptosis

Phospholipase iPLA<sub>2</sub>β averts ferroptosis by eliminating a redox lipid death signal

ProDy 2.0: increased scale and scope after 10 years of protein dynamics modelling with Python

Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation

State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

Orthosteric muscarinic receptor activation by the insect repellent IR3535 opens new prospects in insecticide-based vector control

Collaborators (11)

Wieslaw Nowak

Vladimir Tyurin

Svetlana N Samovich

Valerian E. Kagan

Andrew VanDemark

Haider H. Dar

Bruno Lapied

Qin Yang

Oleksandr Kapralov

Yulia Tyurina

Andrew Amoscato

Make your next move.