Yulia Tyurina

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University of Pittsburgh

United States

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Recent Grants

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Oxygenated Species of Cardiolipins as Biomarkers of Mitochondrial Dysfunction

Open Date: 2011-09-19

Close Date: 2017-06-30

Grant: Close

Signature-Directed, Sequential Delivery of Radiation Mitigators

Open Date: 2005-09-01

Close Date: 2020-08-31

Grant: Close

OXIDATIVE STRESS--CELL OVEREXPRESSING AMYLOID PRECURSOR

Open Date: 1998-06-01

Close Date: 2000-01-01

Articles (14)

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2024

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2023

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2020

Collaborators (16)

Yoel Sadovsky

Director and Professor

Magee-Womens Research Institute

UNITED STATES

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Vladimir Tyurin

University of Pittsburgh

UNITED STATES

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Catalina Pineda Molina

University of Pittsburgh

UNITED STATES

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Svetlana N Samovich

Assistant Professor

Columbia University

UNITED STATES

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Valerian E. Kagan

Professor

University of Pittsburgh

UNITED STATES

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Andrew VanDemark

University of Pittsburgh

UNITED STATES

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Cara Donahue Carey

University of Pittsburgh

UNITED STATES

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Haider H. Dar

University of Pittsburgh

UNITED STATES

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YINGSHI OUYANG

Magee-Womens Research Institute

UNITED STATES

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Qin Yang

University of Pittsburgh

UNITED STATES

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Oleksandr Kapralov

University of Pittsburgh

UNITED STATES

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Karolina Mikulska-Ruminska

Assistant Professor

Nicolaus Copernicus University

POLAND

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Yoojin Lee

University of Pittsburgh

UNITED STATES

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Andrew Amoscato

University of Pittsburgh

UNITED STATES

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Koen Augustyns

Full Professor

University of Antwerp

BELGIUM

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Hülya Bayir

University of Pittsburgh

UNITED STATES

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Yulia Tyurina

Research Interests

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Recent Grants

Articles (14)

Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.

Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators

The lipase cofactor CGI58 controls placental lipolysis.

Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis.

Vitamin E/Coenzyme Q-Dependent "Free Radical Reductases:" Redox Regulators in Ferroptosis.

Membrane regulation of 15LOX-1/PEBP1 complex prompts the generation of ferroptotic signals, oxygenated PEs

Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression

Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome

Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production.

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney.

Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

Lipidomics and RNA sequencing reveal a novel subpopulation of nanovesicle within extracellular matrix biomaterials

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death

Collaborators (16)

Yoel Sadovsky

Vladimir Tyurin

Catalina Pineda Molina

Svetlana N Samovich

Valerian E. Kagan

Andrew VanDemark

Cara Donahue Carey

Haider H. Dar

YINGSHI OUYANG

Qin Yang

Oleksandr Kapralov

Karolina Mikulska-Ruminska

Yoojin Lee

Andrew Amoscato

Koen Augustyns

Hülya Bayir

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