Anna Mascellani Bergo

Czech University of Life Sciences Prague
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Articles (16)

Year:

2024

Five putrescine and spermidine derivatives (1–5) together with five rotenoids (6–10) were isolated from a methanolic extract of the flowers of A. fruticosa that displayed promising inhibition of 76.0 ± 1.9% for AChE and 90.0 ± 4.0% for BuChE at a concentration of 1 mg/mL. Although the anticholinesterase activities of the isolated compounds did not reach that of galantamine, molecular docking revealed that all-trans-tri-p-coumaroylspermidine and trans-trans-cis-tri-p-coumaroylspermidine showed binding poses mimicking the known inhibitor galantamine and thus could serve as model molecules in future searches for new AChE and BuChE inhibitors.

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

Year:

2021

Collaborators (26)

Ondrej Cinek

Professor

Charles University

CZECH REPUBLIC
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Jan Schwarz

Charles University, Faculty of Medicine in Pilsen

CZECH REPUBLIC
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Filip Mercl

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Vit Neuman

-

CZECH REPUBLIC
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Svatopluk Henke

Assistant Professor

University of Chemistry and Technology

CZECH REPUBLIC
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Pavel Tlustos

Prof.

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Tersia Needham

Associate Professor

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Antonella Castagna

associate professor

University of Pisa

ITALY
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Jaroslav Havlik

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Pavel Kloucek

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Richard Hansen

Clinical Reader in Child Health

University of Dundee

UNITED KINGDOM
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Kateřina Valentová

Head of the Laboratory

Institute of Microbiology

CZECH REPUBLIC
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Johana Rondevaldova

Czech University of Life Sciences Prague

CZECH REPUBLIC
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GIACOMO PALAI

University of Pisa

ITALY
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Matěj Božik

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Giovanni Caruso

University of Pisa

ITALY
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Pavel Novy

Czech University of Life Sciences Prague

CZECH REPUBLIC
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Milan Malaník

Masaryk University

CZECH REPUBLIC
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Jakub Treml

Masaryk University

CZECH REPUBLIC
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Jakub Hurych

Charles University

CZECH REPUBLIC
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Rudolf Horváth

Department head

University Hospital in Motol

CZECH REPUBLIC
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Ladislav Kokoska

Full Professor

-

CZECH REPUBLIC
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Petr Marsik

Czech University of Life Sciences Prague

CZECH REPUBLIC
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S W F Milling

University of Glasgow

UNITED KINGDOM
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Konstantinos Gkikas

University of Glasgow

UNITED KINGDOM
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Martin Kamler

Institute for Bee Research

CZECH REPUBLIC
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