Bart L. Haagmans

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Principal Investigator / Associate Professor - PhD

Erasmus MC

Netherlands

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Bart L. Haagmans is a Principal Investigator and Associate Professor at Erasmus MC in the Netherlands. His research areas include the study of coronavirus infections, organoid models for respiratory viruses, and the immunogenicity of vaccines against MERS-CoV. Recent articles authored by him highlight significant advancements in understanding viral transmission, immune responses, and pathogenesis related to SARS-CoV-2 and other respiratory viruses.

Recent Grants

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SARS-CoV-2 Assessment of Viral Evolution (SAVE) Program

Open Date: 2022-01-01

Close Date:

Grant: Close

Safety and efficacy of SARS-CoV-2 antibodies

Open Date: 2020-04-24

Close Date:

Grant: Close

Monoclonal Antibodies against 2019-New Coronavirus - MANCO

Open Date: 2020-03-01

Close Date: 2022-05-01

Grant: Close

Rapid European COVID-19 Emergency Response research (RECOVER)

Open Date: 2020-02-01

Close Date: 2022-02-01

Grant: Close

Improved Vaccination Strategies for Older Adults - ISOLDA

Open Date: 2020-01-01

Close Date: 2024-12-01

Bart L. Haagmans

Research Interests

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About

Recent Grants

Articles (29)

Human organoid models to study coronavirus infections of the respiratory tract.

The role of gowns in preventing nosocomial transmission of respiratory viruses: a systematic review.

Long-term culture of chicken tracheal organoids for the purpose of avian influenza virus research.

Variable DPP4 expression in multiciliated cells of the human nasal epithelium as a determinant for MERS-CoV tropism.

A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.

Dissecting humoral immune responses to an MVA-vectored MERS-CoV vaccine in humans using a systems serology approach

Resistance to SARS-CoV-2 infection in camelid nasal organoids is associated with lack of ACE2 expression

Identification of a Spike-Specific CD8+ T-Cell Epitope Following Vaccination Against the Middle East Respiratory Syndrome Coronavirus in Humans.

Advancing COVID-19 diagnostics: rapid detection of intact SARS-CoV-2 using viability RT-PCR assay.

Profiling the SARS-CoV-2-specific T-cell response.

Virus neutralization assays for human respiratory syncytial virus using airway organoids.

Direct comparison of SARS-CoV-2 variant specific neutralizing antibodies in human and hamster sera.

Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters

Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays

An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution

Safety, immunogenicity, and optimal dosing of a modified vaccinia Ankara-based vaccine against MERS-CoV in healthy adults: a phase 1b, double-blind, randomised placebo-controlled clinical trial.

A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories

Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters

Detection of Double-Stranded RNA Intermediates During SARS-CoV-2 Infections of Syrian Golden Hamsters with Monoclonal Antibodies and Its Implications for Histopathological Evaluation of In Vivo Studies.

Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface

SARS-CoV-2 Omicron entry is type II transmembrane serine protease-mediated in human airway and intestinal organoid models

Preclinical immunogenicity and protective efficacy of a SARS-CoV-2 RBD-based vaccine produced with the thermophilic filamentous fungal expression system Thermothelomyces heterothallica C1

Correction for Mols et al., “Intestinal Tropism of a Betacoronavirus ( Merbecovirus ) in Nathusius’s Pipistrelle Bat (Pipistrellus nathusii), Its Natural Host”

The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells.

Mpox virus infects and injures human kidney organoids, but responding to antiviral treatment

Mpox virus infects and injures human kidney organoids, but responding to antiviral treatment

ICTV Virus Taxonomy Profile: <i>Coronaviridae</i> 2023.

Brief Report: Monkeypox Virus Cross-Neutralizing Antibodies in Clinical Trial Subjects Vaccinated with Modified Vaccinia Virus Ankara Encoding MERS-Coronavirus Spike Protein

Intestinal Tropism of a Betacoronavirus (<i>Merbecovirus</i>) in Nathusius's Pipistrelle Bat (<i>Pipistrellus nathusii</i>), Its Natural Host.

Collaborators (22)

Volker Thiel

Leonie Marie Weskamm

Pengfei Li

Rik De Swart

Giada Mattiuzzo

Gerd Sutter

Janine Kimpel

Luca M. Zaeck

Paul Savelkoul

Lineke Begeman

Mathie Leers

Till Koch

Lisa Bauer

Ron Fouchier

Bart Westendorp

Thijs Kuiken

Derek Smith

Imke Steffen

Juan Manuel Carreno Quiroz

Tim Breugem

Jos van Putten

Anne Voor in 't holt

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