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Brita Singers Sørensen

Aarhus University

Denmark

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Research Interests

Nuclear Physics

80%

Medical Imaging

40%

Radiation Therapy

60%

Ion Irradiation

60%

Accelerator Physics

40%

Radiation Physics

40%

Cancer Biology

40%

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Articles30

Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus.

Article Link

Year:

2025

Preclinical study of reirradiation with hyperthermia in recurrent murine tumors and normal mouse skin

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Year:

2025

Automated acute skin toxicity scoring in a mouse model through deep learning

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Year:

2025

Fixation method influences FLASH skin sparing in an in vivo leg model

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Year:

2025

Electron vs proton FLASH radiation on murine skin toxicity

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Year:

2025

In-vitro and microdosimetric study of proton boron capture therapy and neutron capture enhanced proton therapy

Article Link

Year:

2025

Probing the therapeutic window of proton minibeam radiotherapy using dose-response curves in a mouse model

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Year:

2025

The fractionation effect on proton RBE in a late normal tissue damage model in vivo

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Year:

2025

In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup

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Year:

2025

Hypoxia-induced radioresistance in squamous cell carcinoma of the anus treated with radiotherapy − a validating study

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Year:

2025

Tumor volume and cancer stem cell expression as prognostic markers for high-dose loco-regional failure in head and neck squamous cell carcinoma – A DAHANCA 19 study

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Year:

2024

Development of an Ex Vivo Functional Assay for Prediction of Irradiation Related Toxicity in Healthy Oral Mucosa Tissue

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Year:

2024

Proton FLASH

Article Link

Year:

2024

Oxygen enhancement ratio weighted dose quantitatively describes acute skin toxicity variations in mice after pencil beam scanning proton FLASH irradiation with changing doses and time structures

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Year:

2024

Correlation between local instantaneous dose rate and oxygen pressure reduction during proton pencil beam scanning irradiation

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Year:

2024

Navigating the Critical Translational Questions for Implementing FLASH in the Clinic

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Year:

2024

Two-dimensional time-resolved scintillating sheet monitoring of proton pencil beam scanning FLASH mouse irradiations

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Year:

2024

Evaluation of in vitro irradiation setup

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Year:

2024

Combination of proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers

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Year:

2024

Spread-out Bragg peak FLASH

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Year:

2024

An experimental setup for proton irradiation of a murine leg model for radiobiological studies

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Year:

2023

Pencil beam scanning proton FLASH maintains tumor control while normal tissue damage is reduced in a mouse model

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Year:

2022

A systematic review of clinical studies on variable proton Relative Biological Effectiveness (RBE)

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Year:

2022

Circulating cell-free DNA as predictor of pathological complete response in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy

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Year:

2022

Clinical use and future requirements of relative biological effectiveness

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Year:

2022

The current status of preclinical proton FLASH radiation and future directions

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Year:

2022

Time structure of pencil beam scanning proton FLASH beams measured with scintillator detectors and compared with log files

Article Link

Year:

2022

Total cell-free DNA measurement in metastatic colorectal cancer with a fast and easy direct fluorescent assay

Article Link

Year:

2022

In vivo validation and tissue sparing factor for acute damage of pencil beam scanning proton FLASH

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Year:

2022

Therapeutic Modification of Hypoxia

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Year:

2021

Collaborators28

Christian Maare

consultant oncologist, MD, ph.d., Head and Neck Section

DENMARK

Chandan Guha

Professor and Vice Chair

Montefiore Medical Center

UNITED STATES

Jan Alsner

Aarhus University

DENMARK

Jasper Nijkamp

Associate Professor, Head of Innovation

Aarhus University

DENMARK

Jacob Kinggaard Lilja-Fischer

Aarhus University

DENMARK

Nina Frederike Jeppesen Edin

Associate professor

University of Oslo

NORWAY

Fardous Reaz

Aarhus University

DENMARK

Joanne Haviland

Reader in Medical Statistics

Queen Mary University of London

UNITED KINGDOM

Niels Bassler

Professor

Aarhus University

DENMARK

Jacob Johansen

Aarhus University

DENMARK

Dik C. van Gent

Erasmus University Rotterdam

NETHERLANDS

Camilla Kronborg

Aarhus Universitetshospital

DENMARK

Christian Rønn Hansen

Odense University Hospital

DENMARK

Christina Ankjærgaard

Technical University of Denmark

DENMARK

Stijn Keereweer

university medical center rotterdam

NETHERLANDS

Cai Grau

Aarhus University

DENMARK

Linh Tran

University of Wollongong

AUSTRALIA

Ina Grønkjær Laugesen

Aarhus University

DENMARK

jose angelito hardillo

Head and neck surgeon

Erasmus University Medical Center

NETHERLANDS

Armin Lühr

Technische Universität Dortmund

GERMANY

L. Hoffmann

Aarhus University Hospital

DENMARK

Priyanshu Manojkumar Sinha

Aarhus University

DENMARK

Claus E. Andersen

Technical University of Denmark

DENMARK

Manjit Dosanjh

Professor, Senior Advisor for Medical Applications

CERN

SWITZERLAND

Per Rugaard Poulsen

Professor

Aarhus University

DENMARK

Dietmar Siemann

Professor

University of Florida

UNITED STATES

Irina Danilova

Czech Academy of Sciences, Nuclear Physics Institute

CZECH REPUBLIC

Lewis Shi

Associate Professor

The University of Alabama

UNITED STATES

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