Dave Boucher
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Lecturer in Biomedical Science
United KingdomResearch Interests
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About
Dr. Dave Boucher is a Lecturer in Biomedical Science at the University of York, UK. His research focuses on inflammatory caspases, inflammasomes, and their roles in innate immunity, as evidenced by his recent publications exploring their biochemistry and signaling mechanisms. Dr. Boucher's work aims to provide insights into the activation of inflammatory responses in macrophages and the implications for therapies in various diseases.
Recent Grants
Grant: Close
University of Queensland Fellowship
Open Date: 2015-05-01
Close Date: 2018-04-01
Grant: Close
Fonds de recherche du Quebec en Santé Postdoctoral Fellowship
Open Date: 2013-05-01
Close Date: 2015-04-01
Articles (12)
Year:
2025
Year:
2024
Year:
2024
Year:
2024
Year:
2024
We describe bedside-to-bench immunological and genetic elucidation of defective pyroptosis attributable to novel caspase 4 defect mediating pathogen-triggered inflammatory programmed cell death, in the setting of severe pneumonia and abscess-forming melioidosis in an overtly healthy host failing to clear Burkholderia pseudomallei infection, and how targeted adjunctive biological therapy led to a successful outcome.
Year:
2023
Year:
2023
Year:
2022
Year:
2022
Year:
2021
Year:
2020
Year:
2020
Collaborators (10)
Rebecca Coll
The Queen's University Belfast
Larisa Labzin
University of Queensland Institute for Molecular Bioscience
Kate Schroder
University of Queensland
Sabrina Sofia Burgener
Deputy Lab Head
University of Queensland Institute for Molecular Bioscience
Kim S. ROBINSON
Lecturer
University of York
Kaiwen W Chen
Assistant Professor
National University of Singapore (NUS)
Roderick Lim
Associate Professor
University of Basel
Dimitris Lagos
Professor of Immunology
University of York
Alina Vitak
William Harvey Research Institute
Louis Yi Ann Chai
National University Health System
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