Rebecca Coll

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The Queen's University Belfast

United Kingdom

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Recent Grants

Grant: Close

New Investigator Research Grant

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Target Advancement Program

Open Date: 2021-05-01

Close Date: 2022-05-01

Grant: Close

Springboard Award

Open Date: 2020-10-01

Close Date: 2022-10-01

Grant: Close

Research Grant

Open Date: 2020-03-01

Close Date: 2021-09-01

Grant: Close

Investigating the regulation of the human NLRP3 inflammasome - awarded but declined

Open Date: 2019-01-01

Close Date:

Articles (14)

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2025

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2021

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2020

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2020

Collaborators (11)

Sergi Cuartero

Josep Carreras Leukaemia Research Institute

SPAIN

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Avril Robertson

Affiliate Professor

University of Queensland

AUSTRALIA

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Puja mehta

University College London

UNITED KINGDOM

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Pablo Pelegrin

SPAIN

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Kate Schroder

University of Queensland

AUSTRALIA

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Sabrina Sofia Burgener

Deputy Lab Head

University of Queensland Institute for Molecular Bioscience

AUSTRALIA

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Miguel Valvano

Professor, Chair in Microbiology and Infectious Diseases

The Queen's University Belfast

UNITED KINGDOM

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Manu Shankar-Hari

University of Edinburgh

UNITED KINGDOM

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Romit Samanta

NIHR Clinical Lecturer in Intensive Care Medicine

University of Cambridge

UNITED KINGDOM

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Dave Boucher

Lecturer in Biomedical Science

University of York

UNITED KINGDOM

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Alina Vitak

William Harvey Research Institute

AUSTRALIA

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Rebecca Coll

Research Interests

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Recent Grants

Articles (14)

Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action

Author Correction: Inflammasome components as new therapeutic targets in inflammatory disease

Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease

Inflammasome components as new therapeutic targets in inflammatory disease

The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome

Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation

The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes

Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS)

NLRP3 and pyroptosis blockers for treating inflammatory diseases

Caging NLRP3 tames inflammasome activity

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma

Design, synthesis and evaluation of an NLRP3 inhibitor diazirine photoaffinity probe

Collaborators (11)

Sergi Cuartero

Avril Robertson

Puja mehta

Pablo Pelegrin

Kate Schroder

Sabrina Sofia Burgener

Miguel Valvano

Manu Shankar-Hari

Romit Samanta

Dave Boucher

Alina Vitak

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