Sabrina Sofia Burgener

Deputy Lab Head

University of Queensland Institute for Molecular Bioscience

Australia

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About

Dr. Sabrina Sofia Burgener is the Deputy Lab Head at The University of Queensland Institute for Molecular Bioscience, Australia. Her research focuses on inflammasome signaling, cell death mechanisms, and the interactions of immune cells. Recent publications include studies on pyroptosis, caspase activity, and the spatiotemporal dynamics of signaling in macrophages.

Articles (12)

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2025

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2024

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2024

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2024

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2023

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (9)

Rebecca Coll

The Queen's University Belfast

UNITED KINGDOM

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Evan Ingley

University of Western Australia

AUSTRALIA

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Richard Lucas

Queensland University of Technology

AUSTRALIA

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Charaf Benarafa

SWITZERLAND

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Larisa Labzin

University of Queensland Institute for Molecular Bioscience

AUSTRALIA

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Kate Schroder

University of Queensland

AUSTRALIA

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Dave Boucher

Lecturer in Biomedical Science

University of York

UNITED KINGDOM

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Robert Ju

University of Queensland

AUSTRALIA

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Alina Vitak

William Harvey Research Institute

AUSTRALIA

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Sabrina Sofia Burgener

Research Interests

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Articles (12)

Spectosis: Dying for a complement.

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome

Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages

Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells.

Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme

Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses

SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages

Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells

Placental inflammasome signaling: Protection for mother and baby.

Chronic cigarette smoke exposure and pneumococcal infection induce oropharyngeal microbiota dysbiosis and contribute to long-lasting lung damage in mice

Placental inflammasome signaling: Protection for mother and baby

The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer's disease.

Collaborators (9)

Rebecca Coll

Evan Ingley

Richard Lucas

Charaf Benarafa

Larisa Labzin

Kate Schroder

Dave Boucher

Robert Ju

Alina Vitak

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