David Chalmers

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MONASH UNIVERSITY

Australia

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Recent Grants

Grant: Close

Resolving and targeting the complex molecular mechanisms underlying GPCR signalling

Open Date: 2018-01-01

Close Date: 2021-01-01

Grant: Close

Targeting novel sites on reverse transcriptase for HIV treatment and prevention

Open Date: 2017-01-01

Close Date: 2019-01-01

Grant: Close

Towards a new class of reverse transcriptase inhibitor for HIV prevention

Open Date: 2014-01-01

Close Date: 2016-01-01

Grant: Close

Structure-based design of inhibitors of PimA - a new target for tuberculosis therapy

Open Date: 2013-01-01

Close Date: 2016-01-01

Grant: Close

Structure-based design of inhibitors of HIV-1 integrase

Open Date: 2013-01-01

Close Date: 2016-12-31

Articles (18)

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2025

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2022

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2021

Collaborators (20)

Eddy Arnold

Rutgers University

UNITED STATES

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Tu Le

RMIT University

AUSTRALIA

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Gilda Tachedjian

Head, Life Sciences Discipline and co-Head of Eliminate HIV

Burnet Institute

AUSTRALIA

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Raymond S. Norton

AUSTRALIA

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Mario Boley

MONASH UNIVERSITY

AUSTRALIA

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Scott Ayton

University of Melbourne

AUSTRALIA

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Elizabeth Yuriev

Associate Professor

MONASH UNIVERSITY

AUSTRALIA

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Colin Pouton

MONASH UNIVERSITY

AUSTRALIA

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Bradley Hoare

University of Melbourne

AUSTRALIA

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Mohammed Hossain

University of Melbourne

AUSTRALIA

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Stephen Headey

RMIT University

AUSTRALIA

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Philip Thompson

Monash Institute of Pharmaceutical Sciences

AUSTRALIA

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Daniel Scott

Laboratory Head

Florey Institute of Neuroscience and Mental Health

AUSTRALIA

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Celine Valant

MONASH UNIVERSITY

AUSTRALIA

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Bankala Krishnarjuna

MONASH UNIVERSITY

AUSTRALIA

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Peter J. Scammells

MONASH UNIVERSITY

AUSTRALIA

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Christopher MacRaild

MONASH UNIVERSITY

AUSTRALIA

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Irene Yarovsky

Professor

RMIT University

AUSTRALIA

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Samantha J. Richardson

Professor and Associate Dean for Higher Degrees by Research

RMIT University

AUSTRALIA

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Jessica Holien

RMIT University

AUSTRALIA

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David Chalmers

Research Interests

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Recent Grants

Articles (18)

Structuring of Lipid Nanoparticle mRNA Formulations at acidic and physiological pH: X-ray Scattering and Molecular Dynamics Studies

Re-evaluation of Cyclic Peptide Binding to Neurotensin Receptor 1 by Shifting the Peptide Register during Synthesis

Hydrophobicity-Controlled Self-Assembly of Supramolecular Peptide Nanotubes in Water

Identification of a Novel Subtype-Selective α<sub>1B</sub>-Adrenoceptor Antagonist.

The 8-hydroxyquinoline derivative, clioquinol, is an alpha-1 adrenoceptor antagonist

Engineering of Novel Analogues That Are More Receptor-Selective and Potent than the Native Hormone, Insulin-like Peptide 5 (INSL5)

Developing insulin-like peptide 5-based antagonists for the G protein-coupled receptor, RXFP4

Graph Neural Network-Based Molecular Property Prediction with Patch Aggregation

Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates

Molecular Dynamics Simulation Studies of Bile, Bile Salts, Lipid-Based Drug Formulations, and mRNA–Lipid Nanoparticles: A Review

Interaction of the Inhibitory Peptides ShK and HmK with the Voltage-Gated Potassium Channel KV1.3: Role of Conformational Dynamics

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Membrane Permeating Macrocycles: Design Guidelines from Machine Learning

Structural Analysis of the Complex of Human Transthyretin with 3′,5′-Dichlorophenylanthranilic Acid at 1.5 Å Resolution

Structural Features of Iperoxo–BQCA Muscarinic Acetylcholine Receptor Hybrid Ligands Determining Subtype Selectivity and Efficacy

Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate

Computational and Experimental Models of Type III Lipid-Based Formulations of Loratadine Containing Complex Nonionic Surfactants

Cyclosporin Structure and Permeability: From A to Z and Beyond

Collaborators (20)

Eddy Arnold

Tu Le

Gilda Tachedjian

Raymond S. Norton

Mario Boley

Scott Ayton

Elizabeth Yuriev

Colin Pouton

Bradley Hoare

Mohammed Hossain

Stephen Headey

Philip Thompson

Daniel Scott

Celine Valant

Bankala Krishnarjuna

Peter J. Scammells

Christopher MacRaild

Irene Yarovsky

Samantha J. Richardson

Jessica Holien

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