Dylan G. Ryan

United Kingdom

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Articles (12)

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2025

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2025

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (9)

Christian Frezza

Professor of metabolomics in ageing

University of Cologne

GERMANY

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Emily Day

Assistant Professor

University of Western Ontario

CANADA

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Sharadha Dayalan Naidu

University of Dundee

UNITED KINGDOM

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Ayelet Erez

Baylor College of Medicine

UNITED STATES

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Simon Arthur

Professor

University of Dundee

UNITED KINGDOM

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Hiran Prag

The University of Manchester

UNITED KINGDOM

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Alejandro J Brenes

University of Dundee

UNITED KINGDOM

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Stephen Gordon

Dublin City University

IRELAND

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Angus Lamond

Academic, Professor of Biochemistry

University of Dundee

UNITED KINGDOM

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Dylan G. Ryan

Research Interests

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Articles (12)

Macrophages say NO to nucleotide synthesis and salvage instead

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation

Inflammatory mitochondrial nucleic acids as drivers of pathophysiology

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.

Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression.

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response

Metabolic symbiosis in pancreatic cancer

DIA label-free proteomic analysis of murine bone-marrow-derived macrophages

Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages

Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism

IL-10-Mediated Refueling of Exhausted T Cell Mitochondria Boosts Anti-Tumour Immunity.

Collaborators (9)

Christian Frezza

Emily Day

Sharadha Dayalan Naidu

Ayelet Erez

Simon Arthur

Hiran Prag

Alejandro J Brenes

Stephen Gordon

Angus Lamond

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