Erwin Brosens

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Erasmus University Rotterdam

Netherlands

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Recent Grants

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Clipless MR-eye guided planning and follow-up for proton therapy of Uveal Melanoma

Open Date: 2022-01-01

Close Date: 2026-01-01

Grant: Close

Generation of genetically engineered in vivo models for uveal melanoma research to identify and validate therapeutic targets

Open Date: 2022-01-01

Close Date: 2023-01-01

Grant: Close

Circulating tumor cells as a potential biomarker for high-risk uveal melanoma

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

Unravelling uveal melanoma predisposition and development of metastasis

Open Date: 2021-01-01

Close Date: 2022-01-01

Grant: Close

Can metabolomic analysis of peripheral blood after diagnosis prognosticate between high and low risk UM?

Open Date: 2021-01-01

Close Date: 2021-12-01

Articles (23)

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Collaborators (14)

Farhan Akram

Erasmus University Rotterdam

NETHERLANDS

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Meena Balasubramanian

University of Sheffield

UNITED KINGDOM

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Fred Chen

University of Western Australia

AUSTRALIA

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Martine J. Jager

Leiden University Medical Center

NETHERLANDS

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Tarek Meniawy

University of Western Australia

AUSTRALIA

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Hanneke IJsselstijn

Erasmus University Rotterdam

NETHERLANDS

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Bart J. L. Eggen

NETHERLANDS

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Christian Gilissen

Professor of Genome Bioinformatics

Universitair Medisch Centrum Utrecht

NETHERLANDS

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Harmen van de Werken

Assistant Professor Computational Biology & Bioinformatics at the Department of Immunology

Erasmus MC

NETHERLANDS

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Virginie Verhoeven

Erasmus University Rotterdam

NETHERLANDS

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Casper Kersten

Erasmus University Rotterdam

NETHERLANDS

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Marten Poley

Erasmus University Rotterdam

NETHERLANDS

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Dion Paridaens

Erasmus University Rotterdam

NETHERLANDS

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Johannes Marco Schnater

Erasmus University Rotterdam

NETHERLANDS

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Erwin Brosens

Research Interests

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Recent Grants

Articles (23)

Higher AJCC stage at primary tumor diagnosis may predict shorter survival in metastatic uveal melanoma

Genome-wide methylation analysis in patients with proximal hypospadias–a pilot study and review of the literature

Generation of human induced pluripotent stem cell lines (LUMCi051-A,B and LUMCi052-A,B,C) of two patients with Spinocerebellar ataxia type 7

Uveal Melanoma Zebrafish Xenograft Models Illustrate the Mutation Status-Dependent Effect of Compound Synergism or Antagonism

Prediction of molecular subclasses of uveal melanoma by deep learning using routine haematoxylin–eosin‐stained tissue slides

Protein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status

8q Gain Has No Additional Predictive Value in SF3B1MUT Uveal Melanoma but Is Predictive for a Worse Prognosis in Patients with BAP1MUT Uveal Melanoma

ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome

Evaluation of Circulating Tumor DNA as a Liquid Biomarker in Uveal Melanoma

Uveal melanoma modeling in mice and zebrafish

The Impact of Spliceosome Inhibition in <i>SF3B1</i>-Mutated Uveal Melanoma

Common variants increase risk for congenital diaphragmatic hernia within the context of de novo variants

Identification of Rare Variants Involved in High Myopia Unraveled by Whole Genome Sequencing

Detection of metastases using circulating tumour DNA in uveal melanoma.

More than missing neurons: Intestinal fibrosis in Hirschsprung disease

COllaborative Neonatal Network for the first European CPAM Trial (CONNECT): a study protocol for a randomised controlled trial.

Uveal Melanoma Patients Have a Distinct Metabolic Phenotype in Peripheral Blood

Selection of potential targets for stratifying congenital pulmonary airway malformation patients with molecular imaging

Pathogenic Homozygous Mutations in the DBT Gene (c.1174A&gt;C) Result in Maple Syrup Urine Disease in a rs12021720 Carrier

Pathogenic Homozygous Mutations in the DBT Gene (c.1174A > C) Result in Maple Syrup Urine Disease in a rs12021720 Carrier

Recommendations for whole genome sequencing in diagnostics for rare diseases

FOXD1 Is a Transcription Factor Important for Uveal Melanocyte Development and Associated with High-Risk Uveal Melanoma

High C-Reactive Protein Levels Are Related to Better Survival in Patients with Uveal Melanoma

Collaborators (14)

Farhan Akram

Meena Balasubramanian

Fred Chen

Martine J. Jager

Tarek Meniawy

Hanneke IJsselstijn

Bart J. L. Eggen

Christian Gilissen

Harmen van de Werken

Virginie Verhoeven

Casper Kersten

Marten Poley

Dion Paridaens

Johannes Marco Schnater

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Pathogenic Homozygous Mutations in the DBT Gene (c.1174A>C) Result in Maple Syrup Urine Disease in a rs12021720 Carrier