Francis Impens

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Associate Professor

Ghent University

Belgium

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Francis Impens is an Associate Professor at Ghent University in Belgium. His research areas focus on proteomics, immunopeptidomics, and biomarker discovery, as indicated by his recent work on blood proteome profiling and mRNA vaccine development. His contributions include comprehensive studies on quality control in mass spectrometry and the response of broiler chickens to intestinal health challenges.

Recent Grants

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Integrated platform to validate vesicular trafficking-associated processes in neurodegenerative diseases

Open Date: 2017-06-01

Close Date: 2021-05-01

Grant: Close

Integrated platform to validate vesicular trafficking-associated processes in neurodegenerative diseases

Open Date: 2017-06-01

Close Date: 2021-05-01

Grant: Close

The Interferon Stimulated Gene 15 (ISG15) modification system in host pathogen interactions: Mechanisms, technology and translational potential

Open Date: 2017-04-01

Close Date: 2020-03-01

Grant: Close

The Interferon Stimulated Gene 15 (ISG15) modification system in host pathogen interactions: Mechanisms, technology and translational potential

Open Date: 2017-04-01

Close Date: 2020-03-01

Grant: Close

Proteomics-based characterization of the protein interplay between pathogenic bacteria and their host

Open Date: 2016-10-01

Close Date: 2021-09-01

Francis Impens

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (30)

Proteomics- and metabolomics-based analysis of the regulation of germination in Norway maple and sycamore embryonic axes

A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities.

Blood proteome profiling for biomarker discovery in broilers with necrotic enteritis

Challenges and opportunities in mRNA vaccine development against bacteria

Collisional cross-section prediction for multiconformational peptide ions with IM2Deep

Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken.

Immunopeptidomics identified antigens for mRNA-lipid nanoparticle vaccines with alpha-galactosylceramide in multiple myeloma therapy

Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring

Proteomic profiling of dysbiosis-challenged broilers reveals potential blood biomarkers for intestinal health.

Target acquired: Lock-on bacterial immunopeptides.

SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains

Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria

Benefit of in silico predicted spectral libraries in data-independent acquisition data analysis workflows

High-throughput nanoflow proteomics using a dual-column electrospray source

ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.

Systematic review and meta-analysis of genome-wide pooled CRISPR screens to identify host factors involved in influenza A virus infection.

The association of protein-bound methionine sulfoxide with proteomic basis for aging in beech seeds

Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins

CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity

CysQuant : simultaneous quantification of cysteine oxidation and protein abundance using data dependent or independent acquisition mass spectrometry

Cells Responding to Closely Related Cholesterol-Dependent Cytolysins Release Extracellular Vesicles with a Common Proteomic Content Including Membrane Repair Proteins

A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A.

Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions.

The Final Maturation State of β-actin Involves N-terminal Acetylation by NAA80, not N-terminal Arginylation by ATE1.

Proteome Profiling of RNF213 Depleted Cells Reveals Nitric Oxide Regulator DDAH1 Antilisterial Activity.

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection.

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.

Proteomics Mapping of the ISGylation Landscape in Innate Immunity.

Collaborators (28)

Glenn Vergauwen

Ewa Kalemba

Lilliana Radoshevich

Cláudio Alexandre Almeida Pinheiro

Andreas Damianou

Jennifer Kirwan

Alexander Botzki

Patrick Scheerer

Bart Vandekerckhove

Michael Mülleder

Ine Lentacker

Vadim Demichev

Sandra Sousa

Lorenzo Franceschini

Pieter Mestdagh

Antje Beling

Xavier Saelens

Georges Leclercq

Nele Festjens

van-son nguyen

Arne Janssens

Eva Katrin Wirth

Deeksha Munnur

Lars Scharff

Han Remaut

Serge Plaza

Kim De Veirman

Evy Goossens

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