Frank Leebeek

Erasmus University Rotterdam

Netherlands

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Articles (20)

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2025

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2023

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2023

Collaborators (12)

Flora Peyvandi

Università degli Studi di Torino

ITALY

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Roger Preston

Lecturer in Vascular Biology

IRELAND

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James Dahlman

Associate Professor

Emory University School of Medicine

UNITED STATES

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Cecile Denis

INSERM

FRANCE

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Lize F. D. van Vulpen

NETHERLANDS

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Ruben Bierings

NETHERLANDS

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Martijn Brands

University of Amsterdam

NETHERLANDS

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Nigel Key

Harold R Roberts Distinguished Professor

University of North Carolina

UNITED STATES

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Miguel Escobar

Professor (Tenure)

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Rolf Urbanus

Associate professor

University Medical Center Groningen

NETHERLANDS

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Samantha C. Gouw

NETHERLANDS

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Jeroen Eikenboom

Leiden University Medical Center

NETHERLANDS

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Frank Leebeek

Research Interests

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Articles (20)

Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs

Clinical phenotype and pathophysiological mechanisms underlying qualitative Low VWF.

Von Willebrand disease-specific defects and proteomic signatures in endothelial colony forming cells

A rapid whole-blood adenosine triphosphate secretion test can be used to exclude platelet-dense granule deficiency

The severe von Willebrand disease variant p.M771V leads to impaired anterograde trafficking of von Willebrand factor in patient-derived and base-edited endothelial colony-forming cells

Completion of phase 2b trial of etranacogene dezaparvovec gene therapy in patients with hemophilia B over 5 years

Mild or moderate hemophilia is not always a mild or moderate bleeding disorder

Sexuality and bleeding in von Willebrand disease

Replacement therapy in pregnant women with von Willebrand disease during delivery

Early Postoperative Changes in Von Willebrand Factor Activity Are Associated With Future Bleeding and Stroke in HeartMate 3 Patients

Prophylaxis with recombinant von Willebrand factor in patients with type 3 von Willebrand disease: Results of a post hoc analysis from a phase 3 trial

Transition readiness among adolescents and young adults with haemophilia in the Netherlands

Quantitative super-resolution imaging of platelet degranulation reveals differential release of von Willebrand factor and von Willebrand factor propeptide from alpha-granules

A factor IX variant that functions independently of factor VIII mitigates the hemophilia A phenotype in patient plasma

Antithrombotic Treatment in Patients With Hemophilia

Colorectal cancer screening in patients with inherited bleeding disorders

Patients’ and health care providers’ perspectives on quality of hemophilia care in the Netherlands

von Willebrand factor neutralizing and non-neutralizing alloantibodies in 213 subjects with type 3 von Willebrand disease enrolled in 3WINTERS-IPS

The state of oral health in patients with haemophilia in the Netherlands

Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B

Collaborators (12)

Flora Peyvandi

Roger Preston

James Dahlman

Cecile Denis

Lize F. D. van Vulpen

Ruben Bierings

Martijn Brands

Nigel Key

Miguel Escobar

Rolf Urbanus

Samantha C. Gouw

Jeroen Eikenboom

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