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Gianni D Angelini

United Kingdom

Research Interests

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Professors in United Kingdom

Articles (10)

Year:

2026

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2026

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2026

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2026

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2026

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2025

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2025

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2025

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2025

OBJECTIVES This nationwide retrospective cohort study assessed the impact of the explanted valve type on reoperative outcomes in aortic valve surgery within the UK over a 23-year period. METHODS Data were sourced from the National Institute for Cardiovascular Outcomes Research (NICOR) database. All patients undergoing first-time isolated reoperative aortic valve replacement between 1996 and 2019 in the UK were included. Concomitant procedures, homograft implantation or aortic root enlargement were excluded. Propensity score matching was utilized to compare outcomes and risk factors for in-hospital mortality was evaluated through multivariable logistic regression. Final model selection was conducted using Akaike Information Criterion through bootstrapping. The primary end point was in-hospital mortality, and secondary end points included postoperative morbidities. RESULTS Out of 2371 patients, 24.9% had mechanical and 75% had bioprosthetic valves implanted during the primary procedure. Propensity matched groups of 324 patients each, were compared. In-hospital mortality for mechanical and bioprosthetic valve explants was 7.1% and 5.9%, respectively (P = 0.632). On multivariable logistic regression analysis, valve type was not a risk factor for mortality [odds ratio (OR) 0.62, 95% confidence interval (CI) 0.37–1.05; P = 0.1]. Age (OR 1.03, 95% CI 1.01–1.05; P < 0.05), left ventricular ejection fraction (OR 1.62, 95% CI 1.08–2.42; P < 0.05), creatinine ≥ 200 mg/dl (OR 2.21, 95% CI 1.17–4.04; P < 0.05) and endocarditis (OR 2.66, 95% CI 1.71–4.14; P < 0.05) emerged as risk factors for mortality. CONCLUSIONS The type of valve initially implanted (mechanical or bioprosthetic) did not determine mortality. Instead, age, left ventricular ejection fraction, renal impairment and endocarditis were significant risk factors for in-hospital mortality.

Year:

2024

Collaborators (126)

Simon Erridge

University College London

UNITED KINGDOM

Gianni D Angelini

Research Interests

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Articles (10)

30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studies

Five-Year Hospital Readmission After Isolated Coronary Artery Bypass Grafting in the United Kingdom

National trends, variation and short-term outcomes in surgery for non-small cell lung cancer in England, 2015-2023: a population-based cohort study using linked national cancer registration and hospital administrative data.

Utilisation patterns of systemic anticancer therapy (SACT) in patients with advanced non-small cell lung cancer (NSCLC) in England.

Worse risk profile, number of grafts and hospital death but acceptable late survival in females undergoing coronary surgery: a 20-year propensity matched analysis

The National Cancer Audit Collaborating Centre (NATCAN): improving the quality of National Health Service cancer care in England and Wales

Sublobar resection or lobectomy for stage Ia non-small cell lung cancer: a systematic review and meta-analysis

The expanding role for national cancer audits supporting quality improvement in the NHS

Temporal Trends in Outcomes and Predictors of Length of Stay Following Lung Cancer Resection Over 10 Years With Enhanced Recovery After Surgery

Impact of explanted valve type on aortic valve reoperations: nationwide UK experience

Collaborators (126)

Simon Erridge

James Glasbey

Marcello Di Martino

Jacobo Trebol

Dickon Hayne

Filipe Manuel Paiva dos Santos

Matteo Marro

Anton Lambers

Berta Díaz-Feijoo

Alberto G Barranquero

Abd Jabar Nazimi

Andreas Älgå

Evripidis Tokidis

Philipp Foessleitner

Alex Alfieri

Thomas E Cowling

Julio Mayol

Sivesh K Kamarajah

Krystel Nyangoh Timoh

Alan Norrish

Pierpaolo Sileri

Luca Bruschini

Rahel Ghebre

Kayani Kayani

Nolan Bruce

André Leite-Moreira

Maciej Walędziak

ONA BLOOM

David Bosanquet

Jasper Stijns

Daniele Bissacco

Maria Picciochi

Alfredo Annicchiarico

Zbigniew Lorenc

Daniele Sambucci

Carlos A Toro

Teofila Bueser

Stefano Piero Bernardo Cioffi

Veeru Kasivisvanathan

Michael McTague

Jeremy Chan

DIETER MORALES-GARCIA

Maurizio Domanin

Wiktor Krawczyk

CHRISTOS KONTOVOUNISIOS

Matteo ZOLI

Liliana Mereu

Tommaso Violante

Humberto Fenner Lyra Junior

Marissa Boeck

Ahmad Ozair

Michael Jenkinson

Hooman Soleymani majd

Antonios Gklavas

Kate Jolly

VALERIA TONINI

Alfredo Conti

Hemant M Kocher

Fabio Martinelli

Cristina Ojeda-Thies

Andrew Loehrer

Francesco Fleres

Rachel Vogel

Jo Morrison