Irene H. Heijink
NetherlandsResearch Interests
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Articles (6)
Year:
2025
Year:
2023
To our knowledge, this is the first study investigating the role of the COPD susceptibility gene FAM13A in aging and cellular senescence. We found that FAM13A negatively regulates the expression of the cellular senescence marker P21 and mitochondrial ROS production in the airway epithelium. In this way, the lower expression of FAM13A observed upon aging may facilitate cellular senescence and potentially contribute to accelerated lung aging in COPD.
Year:
2023
Year:
2022
Year:
2022
Year:
2022
Collaborators (10)
Simon Pouwels
University of Groningen
Korneliusz Golebski
Amsterdam University Medical Centers
Anne van der Does
Assistant Professor
Leiden University Medical Center
Tania Maes
Associate Professor
Universiteit Gent
Christoph Beisswenger
Saarland University
Machteld N. Hylkema
University of Groningen
Stefan Andreas
Head
-
Anke Maitland-van der Zee
Prof. Precision Medicine in Respiratory Disease
Amsterdam UMC Locatie AMC
Harm Jan Bogaard
-
Pieter Hiemstra
Professor of Respiratory cell Biology and Immunology
Leiden University Medical Center
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