Anne van der Does

Assistant Professor

Leiden University Medical Center

Netherlands

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About

Anne van der Does is an Assistant Professor at Leiden University Medical Center in the Netherlands. Her research focuses on inflammation, viral infections, and the molecular responses of airway epithelial cells, particularly in the context of COVID-19 and other pulmonary conditions. Recent publications highlight her work on cytokine storms, interferon responses, and epithelial cell behavior in various disease states.

Articles (17)

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2020

Collaborators (25)

Simon Pouwels

University of Groningen

NETHERLANDS

Anne van der Does

Research Interests

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About

Articles (17)

Loss of Pulmonary Endothelial Cells in Emphysema Impairs Support of Human Alveolar Epithelial Cell Growth

Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease.

SARS-CoV-2-infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses.

Human host defence peptide LL-37 suppresses TNFα-mediated matrix metalloproteinases MMP9 and MMP13, in human bronchial epithelial cells.

ERS International Congress 2023: highlights from the Basic and Translational Sciences Assembly.

ERS international Congress 2022: highlights from the Basic and Translational Science Assembly

Precision Medicine for More Oxygen (P4O2)—Study Design and First Results of the Long COVID-19 Extension

Isolating Bronchial Epithelial Cells from Resected Lung Tissue for Biobanking and Establishing Well-Differentiated Air-Liquid Interface Cultures.

Impact of changes in human airway epithelial cellular composition and differentiation on SARS-CoV-2 infection biology.

Airway epithelial cells mount an early response to mycobacterial infection

IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels.

Acute cigarette smoke exposure leads to higher viral infection in human bronchial epithelial cultures by altering interferon, glycolysis and GDF15-related pathways.

Breathing on chip: Dynamic flow and stretch accelerate mucociliary maturation of airway epithelium <i>in vitro</i>.

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

Organoid-based expansion of patient-derived primary alveolar type 2 cells for establishment of alveolus epithelial Lung-Chip cultures

Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa

Impact of the Local Inflammatory Environment on Mucosal Vitamin D Metabolism and Signaling in Chronic Inflammatory Lung Diseases.

Collaborators (25)

Simon Pouwels

Anna H.E. Roukens

Annemieke Geluk

Korneliusz Golebski

Senani Rathnayake

Jasmijn Schrumpf

Mareike Lehmann

Simon Jochems

Natalia El-Merhie

Katharine Lodge

P. Padmini J. S. Khedoe

Matthew Loxham

Christian Taube

Irene H. Heijink

Jutte J.C. de Vries

Anke Maitland-van der Zee

Frank Staal

Simone A Joosten

Harm Jan Bogaard

Sara Rolandsson Enes

Bernard van den Berg

Eric Snijder

Lareb Dean

Pieter Hiemstra

Natacha Ogando

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