Jack Green

The University of Manchester

United Kingdom

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Articles (15)

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2024

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2024

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2020

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2020

Collaborators (18)

Richard Bryce

The University of Manchester

UNITED KINGDOM

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Thomas Liman

Charité - Universitätsmedizin Berlin

GERMANY

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Sonsoles Hortelano

Head of Unit

Instituto de Salud Carlos III

SPAIN

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Fatima Martin-Sanchez

Assistant Professor Doctor

Universidad de Murcia

SPAIN

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Sally Freeman

Lecturer, Senior Lecturer Reader

The University of Manchester

UNITED KINGDOM

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Tessa Swanton

The Francis Crick Institute

UNITED KINGDOM

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Martin Lowe

UNITED KINGDOM

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Catherine Lawrence

Senior Lecturer

The University of Manchester

UNITED KINGDOM

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Douglas Dyer

The University of Manchester

UNITED KINGDOM

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Ruben Barroso

The University of Manchester

UNITED KINGDOM

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Andrew Leach

The University of Manchester

UNITED KINGDOM

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Ingo Schiessl

The University of Manchester

UNITED KINGDOM

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Gloria López-Castejón

The University of Manchester

UNITED KINGDOM

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Stuart Allan

Professor of Neuroscience

The University of Manchester

UNITED KINGDOM

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Antony Adamson

The University of Manchester

UNITED KINGDOM

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Kevin Couper

Professor

The University of Manchester

UNITED KINGDOM

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Christopher Hoyle

The University of Manchester

UNITED KINGDOM

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David Brough

The University of Manchester

UNITED KINGDOM

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Jack Green

Research Interests

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Articles (15)

The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome.

Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome

Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke

Lymphatic network drainage resolves cerebral oedema and facilitates recovery from experimental cerebral malaria

Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome

Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors

Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome

LRRC8A is dispensable for a variety of microglial functions and response to acute stroke

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages

Looking into the IL-1 of the storm: are inflammasomes the link between immunothrombosis and hyperinflammation in cytokine storm syndromes?

Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification

Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation.

LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl- channel modulation

Collaborators (18)

Richard Bryce

Thomas Liman

Sonsoles Hortelano

Fatima Martin-Sanchez

Sally Freeman

Tessa Swanton

Martin Lowe

Catherine Lawrence

Douglas Dyer

Ruben Barroso

Andrew Leach

Ingo Schiessl

Gloria López-Castejón

Stuart Allan

Antony Adamson

Kevin Couper

Christopher Hoyle

David Brough

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