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Jason Rosch

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St. Jude Children's Research Hospital

United States

Research Interests

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Professors in United States Professors in Microbiology Microbiology professors in United States

Recent Grants

Grant: Open

[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell disease

Open Date: 2025-02-26

Close Date: 2029-01-31

Grant: Close

Trivalent Live Attenuated Vaccines for Bacterial Acute Otitis Media

Open Date: 2024-02-01

Close Date: 2025-12-31

Grant: Close

Characterization of TCS11 in Streptococcus pneumoniae

Open Date: 2024-02-01

Close Date: 2025-12-31

Grant: Close

Attacking failure of antibiotic treatment by targeting antimicrobial resistance enabler cell-states

Open Date: 2022-09-12

Close Date: 2026-06-30

Grant: Open

Evolvable essentiality in the pan-genome of Streptococcus pneumoniae and its mechanistic and evolutionary consequences

Open Date: 2022-07-01

Close Date: 2027-06-30

Articles (19)

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UNITED STATES

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N. Luisa Hiller

Associate Professor

Carnegie Mellon University

UNITED STATES

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University of Tennessee Health Science Center

UNITED STATES

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Christopher McDevitt

Professor

University of Melbourne

AUSTRALIA

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Jason Rosch

Research Interests

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Recent Grants

Articles (19)

Non-cell-autonomous tumor promotion in<i> DICER1</i> cancer predisposition

Pre-treatment bacterial cell states shape antibiotic-induced transcriptional reprogramming and survival

Resistance, heteroresistance, and fitness costs drive colistin treatment failure during Acinetobacter baumannii pneumonia

Naturally acquired promoter variation influences Streptococcus pneumoniae infection outcomes

Mechanisms of 10-hydroxyoctadecanoic acid resistance in Streptococcus pneumoniae

Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus.

Lipoteichoic acid mediates binding of Streptococcus pneumoniae and influenza A virus

Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

Peptide maturation molecules act as molecular gatekeepers to coordinate cell-cell communication in Streptococcus pneumoniae

Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

Staphylococcus aureus oleate hydratase produces ligands that activate host PPARα.

Convergent impact of vaccination and antibiotic pressures on pneumococcal populations

A Trivalent Live Vaccine Elicits Cross-Species Protection Against Acute Otitis Media in a Murine Model

Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of &lt;i&gt;Streptococcus pneumoniae&lt;/i&gt;.

The role of CopA in Streptococcus pyogenes copper homeostasis and virulence

Oligopeptide Transporters of Nonencapsulated Streptococcus pneumoniae Regulate CbpAC and PspA Expression and Reduce Complement-Mediated Clearance

Magnetic bead-based separation of pneumococcal serotypes

Isolation and Characterization of a Novel Alpha-Hemolytic &lt;i&gt;Streptococcus&lt;/i&gt; spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice.

Airway proteolytic control of pneumococcal competence

Collaborators (17)

Vaughn Cooper

Jason Hanna

Daniel Neill

James Conway

Mark Hatley

Elisa Margolis

Lance Keller

Anne L Wyllie

N. Luisa Hiller

Mark Nicol

Elaine Tuomanen

Larry McDaniel

Richard E Lee

Michael Johnson

Christopher Radka

Bernd Meibohm

Christopher McDevitt

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Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of <i>Streptococcus pneumoniae</i>.

Isolation and Characterization of a Novel Alpha-Hemolytic <i>Streptococcus</i> spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice.