John Tregoning

Professor

Imperial College London

United Kingdom

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John Tregoning is a Professor at Imperial College London, UK. His research primarily focuses on immunology, with recent articles exploring the interplay between expression and inflammation in DNA and RNA vaccines, as well as challenges in personalized medicine. He has contributed significantly to the understanding of vaccine development, emphasizing advancements in RNA vaccine technology and immunogenicity.

John Tregoning

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Articles (20)

Modifying non-coding regions of linear DNA vaccines to explore the interplay of expression and inflammation in immunogenicity

Un-personalised medicine: the challenges of vaccines as a single medicine for a whole population

Immunology of RNA-based vaccines: The critical interplay between inflammation and expression

Manipulating the delivery and immunogenicity of DNA vaccines through the addition of CB[8] to cationic polymers

The past, present, and future of RNA vaccines

A sort and sequence approach to dissect heterogeneity of response to a self-amplifying RNA vector in a novel human muscle cell line

A Transgenic Mouse With a Humanized B-Cell Repertoire Mounts an Antibody Response to Influenza Infection and Vaccination

IL-1α is required for T cell-driven weight loss after respiratory viral infection

Recent advances in the influenza virus vaccine landscape: a comprehensive overview of technologies and trials

The tricky second album: Licensure of an mRNA vaccine for respiratory syncytial virus

Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines

LION: Taming RNA vaccine inflammation

Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model

Respiratory syncytial virus after the SARS-CoV-2 pandemic — what next?

Blocking T‐cell egress with FTY720 extends DNA vaccine expression but reduces immunogenicity

Enhanced IL-2 in early life limits the development of TFH and protective antiviral immunity

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

Vaccines for COVID‐19

Pregnancy has a minimal impact on the acute transcriptional signature to vaccination

Respiratory Viral Infection Alters the Gut Microbiota by Inducing Inappetence

Collaborators (10)

Chloe Pyle

Daniel Goldhill

Hannah Cheeseman

Tiina Talts

Jamie Mann

Leah Cuthbertson

Wendy S. Barclay

Clare M. Lloyd

Cecilia Johansson

Michael Cox

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