Marcel Tijsterman

Professor, Groupleader

Leiden University Medical Center

Netherlands

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Articles (12)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

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2022

Year:

2022

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2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (5)

Marcel van Vugt

Principle Investigator/Adjunct Professor

University of Groningen

NETHERLANDS

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Bennie Lemmens

Assistant Professor

Karolinska Institutet

SWEDEN

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Juliette Kamp

Erasmus University Rotterdam

NETHERLANDS

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Marcel den Hoed

Assistant Professor, Docent

Uppsala Universitet Medicinska fakulteten

SWEDEN

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Susan Kloet

Assistant Professor - Head, Leiden Genome Technology Center

Leiden University Medical Center

NETHERLANDS

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Marcel Tijsterman

Research Interests

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Articles (12)

Profiling Cas9‐ and Cas12a‐induced mutagenesis in Arabidopsis thaliana

Genetic dissection of mutagenic repair and T-DNA capture at CRISPR-induced DNA breaks in Arabidopsis thaliana

A light switch for DNA break repair

Chromosomal breaks at the origin of small tandem DNA duplications

POLQ to the rescue for double-strand break repair during mitosis

Distinct mechanisms for genomic attachment of the 5′ and 3′ ends of Agrobacterium T-DNA in plants

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications

Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini

Preservation of lagging strand integrity at sites of stalled replication by Pol α-primase and 9-1-1 complex

BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner

Collaborators (5)

Marcel van Vugt

Bennie Lemmens

Juliette Kamp

Marcel den Hoed

Susan Kloet

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