Mie Kristensen

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Københavns Universitet

Denmark

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Recent Grants

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Human in vitro model til screening af nye lægemidler til levering via næsehulen til behandling af hjernesygdomme

Open Date: 2023-10-01

Close Date: 2024-09-01

Grant: Close

SneakPepBBB: Sneaking peptide drugs into the brain through build-in blood-brain barrier targeting and permeating functionalities

Open Date: 2023-09-01

Close Date: 2026-08-01

Grant: Close

Nose-to-brain: A novel pathway for pharmacological treatment of stroketriggered brain tissue damage

Open Date: 2023-01-01

Close Date: 2023-12-01

Grant: Close

Nose-to-brain: A novel pathway for pharmacological treatment of stroke-triggered brain tissue damage

Open Date: 2022-01-01

Close Date: 2022-12-01

Articles (15)

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2020

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2020

Collaborators (10)

Bente Gammelgaard

Københavns Universitet

DENMARK

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Eduardo Felipe Alves Fernandes

Københavns Universitet

DENMARK

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Lasse Saaby

Københavns Universitet

DENMARK

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Stine Rønholt

Københavns Universitet

DENMARK

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Hans Christian Cederberg Helms

Københavns Universitet

DENMARK

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Birger Brodin

Professor, CNS Drug Delivery

University of Copenhagen

DENMARK

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Annette Burkhart Larsen

Aalborg University

DENMARK

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Anders Bach

Københavns Universitet

DENMARK

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Morten Schallburg Nielsen

Aarhus University

DENMARK

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Ragna Guldsmed Diedrichsen

Københavns Universitet

DENMARK

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Mie Kristensen

Research Interests

Contact this professor

Recent Grants

Articles (15)

The PSD-95 inhibitor NA-1 is delivered to the brain upon nasal administration with uptake into the olfactory bulb improved by co-administration with the cell-penetrating peptides lowPro and Tat

Efficient Generation of Expandable Dorsal Forebrain Neural Rosette Stem Cell Lines

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

Insulin-inspired peptides may open new pathways to treat Alzheimer’s disease

Rodent ischemic stroke models and their relevance in preclinical research

Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action

Selenomethionine as alternative label to the fluorophore TAMRA when exploiting cell-penetrating peptides as blood-brain barrier shuttles to better mimic the physicochemical properties of the non-labelled peptides

Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line

The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

Increased Carrier Peptide Stability through pH Adjustment Improves Insulin and PTH(1-34) Delivery In Vitro and In Vivo Rather than by Enforced Carrier Peptide-Cargo Complexation

Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

Collaborators (10)

Bente Gammelgaard

Eduardo Felipe Alves Fernandes

Lasse Saaby

Stine Rønholt

Hans Christian Cederberg Helms

Birger Brodin

Annette Burkhart Larsen

Anders Bach

Morten Schallburg Nielsen

Ragna Guldsmed Diedrichsen

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