Mohammed Shahait

United Arab Emirates

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Professors in Medical Imaging

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Articles (26)

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2025

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2025

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2025

Glucagon-like peptide-1 (GLP-1), an incretin hormone renowned for its role in post-meal blood sugar regulation and glucose-dependent insulin secretion, has gained attention as a novel treatment for diabetes through GLP-1 receptor agonists (GLP-1-RA). Despite their efficacy, concerns have been raised regarding the potential associations between GLP-1-RA and certain malignancies, including medullary thyroid cancer. However, evidence of its association with prostate cancer (PCa) remains inconclusive. This review delves into the intricate relationship between GLP-1-RA and PCa, exploring the mechanisms through which GLP-1-Rs may impact PCa cells. We discuss the potential pathways involving cAMP, ERK, AMPK, mTOR, and P27. Furthermore, we underscore the imperative for additional research to elucidate the impact of GLP-1-RA treatment on PCa progression, patient outcomes, and potential interactions with existing therapies. Translational studies and clinical trials are crucial for a comprehensive understanding of the role of GLP-1-RA in PCa management.

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (54)

Ahmed A Abdulelah

University of Edinburgh

UNITED KINGDOM

Mohammed Shahait

Research Interests

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Articles (26)

Re: Evaluating PI-RADS lesions and clinically significant prostate cancer in Black and Asian men: a PREVENT randomized clinical trial secondary analysis

Editorial Comment on “Long-term Outcomes of Partial Nephrectomy vs Percutaneous Ablation for Renal Cell Carcinoma: A Propensity-Matched Analysis Type of Article: Original Research”

Gender Disparity in Persian Gulf Urological Conferences Over the Past Three Years

From Diabetes to Oncology: Glucagon-like Peptide-1 (GLP-1) Receptor Agonist’s Dual Role in Prostate Cancer

Propensity Score Matching Analysis of Differential Outcomes in Holmium Laser Enucleation of the Prostate vs. Robotic-Assisted Simple Prostatectomy

Who Are the Mentors of the Future Endourologist? An Analysis of Endourological Society Program Directors

Understanding the Termination of Urologic Cancer Clinical Trials: Insights and Challenges

Assessing Decision Regret in Patients with Same-Day Discharge Pathway After Robot-Assisted Radical Prostatectomy

Factors affecting the non-publication of clinical trials of prevalent urological cancer

A New Era for PET/CT: Applications in Non-Tumorous Renal Pathologies

MRI-based radiomic features of the urinary bladder wall identify patients with moderate-to-severe international prostate symptom score

Bibliometric analysis of focal therapy in prostate cancer research

Quantification and molecular correlates of tertiary lymphoid structures in primary prostate cancer

Instrument failures for the AirSeal device: A Food and Drug Administration MAUDE database study

Urology Practice in Low- to Middle-Income Countries

Post-Graduate Urology Training in Low- and Middle-Income Countries

MRI-Based Radiomics Analysis of Levator Ani Muscle for Predicting Urine Incontinence after Robot-Assisted Radical Prostatectomy

Outcomes of Percutaneous Nephrolithotomy Under Local Anesthesia: Outcomes of a Systematic Review of Literature

Periprostatic Adipose Tissue MRI Radiomics-Derived Features Associated with Clinically Significant Prostate Cancer

Impact of obstructive sleep apnea syndrome on time to complete recovery of continence after robot-assisted radical prostatectomy: A propensity score matching analysis.

Commentary

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.

When to order genomic tests: development and external validation of a model to predict high-risk prostate cancer at the genotypic level

Twenty-four hour urine parameters in nephrolithiasis patients with obstructive sleep apnea syndrome

The Role of Pelvic Exenteration in the Management of Locally Advanced Prostate Cancer

Collaborators (54)

Ahmed A Abdulelah

Mina Youssef

Enoch Akowuah

Bhaskar Somani

Matteo Marro

Michael Farrell

YAMINI SUBRAMANI

Shaikh Sanjid Seraj

Marisa Domingues Santos

David Bosanquet

Jasper Stijns

NICCOLO' DADDI

Adam Frankel

Giandomenico Maggiore

Thomas Pinkney

NIKOLAOS KIRIAKOPOULOS

Ugo Giovanni Falagario

Nicola Colucci

Alvaro Sanchez Barrueco

Georg Singer

Ruben Usamentiaga

Bashir Al Hussein Al Awamlh

David Lee

Ignacio Javier Fernandez

Marc Vallve-Bernal

Rebecka Hultgren

Mahesh Nagappa

Victoriano Soria Aledo

Ioannis Siasios

Andrea Melloni

Pawel Miotla

Cristina Costeira

OLGA MATEO-SIERRA

Joao Goncalo Valverde

Aneel Bhangu

JUAN-CARLOS GOMEZ-ROSADO

Maria P Ntalouka

Tom Abbott

Kai Yuen Wong

JAVIER MATA

Alessia D’Amico

GIAN MARCO PRUCHER

Mohamed Otify

Anil Hormis

Reza Motallebzadeh

Funlayo Odejinmi

David Moszkowicz

Guy Stanley

Marios Ghobrial