Nicholas Pearce

University of Amsterdam

Netherlands

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Articles (12)

Year:

2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Year:

2020

Collaborators (9)

Sven Hennig

University of Amsterdam

NETHERLANDS

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Alan Gerber

Assistant Professor

Amsterdam UMC Locatie AMC Divisie 9

NETHERLANDS

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Loes Kroon-Batenburg

Assistent professor

Utrecht University

NETHERLANDS

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Anouk Rijs

University of Amsterdam

NETHERLANDS

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Elisa Fadda

Associate Professor

University of Southampton

UNITED KINGDOM

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Andrea Thorn

Universität Hamburg

GERMANY

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Tom Grossmann

University of Amsterdam

NETHERLANDS

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Yunyun Gao

Universität Hamburg

GERMANY

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James Fraser

Professor

University of California, San Francisco

UNITED STATES

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Nicholas Pearce

Research Interests

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Articles (12)

Covalent bicyclization of protein complexes yields durable quaternary structures

Up, up, down, down: the structural biology of the SARS-CoV-2 spike protein and how it cheats the immune system

Structural biology of SARS-CoV-1/SARS-CoV-2 main protease

Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data

Experiences From Developing Software for Large X-Ray Crystallography-Driven Protein-Ligand Studies

Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure–activity studies and high-resolution crystal structures

Improving sampling of crystallographic disorder in ensemble refinement

A method for intuitively extracting macromolecular dynamics from structural disorder

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.

Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F

Collaborators (9)

Sven Hennig

Alan Gerber

Loes Kroon-Batenburg

Anouk Rijs

Elisa Fadda

Andrea Thorn

Tom Grossmann

Yunyun Gao

James Fraser

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