Osama Harraz

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Assistant Professor, Tenure Track

University of Vermont

United States

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About

Osama Harraz is an Assistant Professor on the Tenure Track at the University of Vermont, USA. His research focuses on vascular physiology, channelopathies, and the dynamics of blood flow in cerebral networks. Recent publications highlight his work on ion channels, vascular reactivity, and mechanisms of blood flow regulation in neurological contexts.

Recent Grants

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Brain capillary Piezo1 ion channels and blood flow regulation in Alzheimer’s Disease

Open Date: 2023-05-01

Close Date: 2025-04-30

Grant: Close

Vermont Center for Cardiovascular and Brain Health

Open Date: 2020-08-06

Close Date: 2025-05-31

Grant: Close

Mechanosensation in Brain Capillaries

Open Date: 2020-07-01

Close Date: 2023-06-30

Grant: Close

Mechanosensation in Brain Capillaries

Open Date: 2020-07-01

Close Date: 2023-06-30

Grant: Close

Mechanosensation in Brain Capillaries

Open Date: 2020-07-01

Close Date: 2023-06-30

Articles (23)

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2021

Collaborators (16)

Eleonora Grandi

University of California, Davis

UNITED STATES

Osama Harraz

Research Interests

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About

Recent Grants

Articles (23)

Brain Capillary Ion Channels: Physiology and Channelopathies

Estrogen Enhances SK Channel Activity to Limit Hippocampal Arteriole Constriction.

A computational framework for quantifying blood flow dynamics across myogenically-active cerebral arterial networks.

VasoTracker 2: An Open-source Platform for Quantitative Analysis of Vascular Reactivity and Function

Abstract TP252: Modulation of Piezo1 Channels Improves Cerebral Blood Flow in a Mouse Model of Alzheimer&#x27;s Disease.

Vascular Signaling Plasticity – Bidirectional Reshaping of Hemodynamic Control

Recent insights into channelopathies

Distinct potassium channel types in brain capillary pericytes

Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow

Amyloid beta Aβ1-40 activates Piezo1 channels in brain capillary endothelial cells

Evidence of an excitatory purinergic innervation in mouse corpus cavernosum smooth muscle

Diversity of cells and signals in the cardiovascular system

A new model for evaluating pressure-induced vascular tone in small cerebral arteries

Endothelial Cell Metabolism and Vascular Function: A Paradigm Shift?

A new model for evaluating pressure-induced vascular tone in small cerebral arteries

Mechanosensing by Vascular Endothelium

Editorial: Small and mighty: Brain capillaries in health and disease

Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries

Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries.

Vascular calcium signalling and ageing

Vascular calcium signaling and aging

Piezo1 is a mechanosensor channel in CNS capillaries

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease

Collaborators (16)

Eleonora Grandi

David Jones

Nikki Gillum Posnack

Thomas Longden

Nicholas Klug

Sanjay Pant

Fabrice Dabertrand

Donald Bers

Maria Sancho

Dobromir Dobrev

Mark Nelson

Lars Jørn Jensen

Dmitry D Postnov

Rose Dixon

Eric Delpire

Adam Greenstein

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Abstract TP252: Modulation of Piezo1 Channels Improves Cerebral Blood Flow in a Mouse Model of Alzheimer's Disease.