Paolo Arosio

Assistant Professor

ETH-Rat und im ETH-Bereich

Switzerland

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Paolo Arosio is an Assistant Professor at ETH-Rat und im ETH-Bereich in Switzerland. His research focuses on biomolecular condensates and their role in enzymatic reactions, protein aggregation, and extracellular vesicle interactions. Recent articles highlight his contributions to understanding the physico-chemical landscape of biomolecular systems and the real-time observation of protein dynamics.

Paolo Arosio

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Articles (23)

Current practices in the study of biomolecular condensates: a community comment

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Biomolecular condensates as regulators of enzymatic reactions

Enhancement of enzymatic activity by biomolecular condensates through pH buffering

Affinity‐Based Isolation and One‐Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates

Real‐Time Observation of Protein Aggregation at Liquid‐Liquid Interfaces in a Microfluidic Device

In situ analysis of osmolyte mechanisms of proteome thermal stabilization

RNA modulates hnRNPA1A amyloid formation mediated by biomolecular condensates

Local environment in biomolecular condensates modulates enzymatic activity across length scales

The physico-chemical landscape of extracellular vesicles

α-Synuclein Aggregation Is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation

Multiparametric Orthogonal Characterization of Extracellular Vesicles by Liquid Chromatography Combined with In-Line Light Scattering and Fluorescence Detection

High‐Yield Production of Extracellular Vesicle Subpopulations with Constant Quality Using Batch‐Refeed Cultures

AF4 and PEG Precipitation as Predictive Assays for Antibody Self-Association

High‐Yield Separation of Extracellular Vesicles Using Programmable Zwitterionic Coacervates

Surface Passivation Method for the Super-repellence of Aqueous Macromolecular Condensates

A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

Modeling the Structure and Interactions of Intrinsically Disordered Peptides with Multiple Replica, Metadynamics-Based Sampling Methods and Force-Field Combinations

Droplet-Based Microfluidic Temperature-Jump Platform for the Rapid Assessment of Biomolecular Kinetics

Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity

Droplet Microfluidics for the Label‐Free Extraction of Complete Phase Diagrams and Kinetics of Liquid–Liquid Phase Separation in Finite Volumes

Programmable Zwitterionic Droplets as Biomolecular Sorters and Model of Membraneless Organelles

Collaborators (11)

Paolo Bergese

Jonathan Kingsbury

Maria Hondele

Lunna Li

Matteo Salvalaglio

Katarzyna Makasewicz

Paola Picotti

Eric Robert Dufresne

Rumiana Dimova

Zbynek Prokop

Danfeng Cai

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