Patrick M. Sexton

MONASH UNIVERSITY

Australia

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Articles (15)

Year:

2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (13)

Emma van der Westhuizen

MONASH UNIVERSITY

AUSTRALIA

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David M. Thal

AUSTRALIA

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Giuseppe Deganutti

Coventry University

UNITED KINGDOM

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Mario Rossi

University of L'Aquila

ITALY

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Shailesh N. Mistry

UNITED KINGDOM

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Radostin Danev

University of Tokyo

JAPAN

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Arthur Christopoulos

MONASH UNIVERSITY

AUSTRALIA

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Christopher J. Langmead

MONASH UNIVERSITY

AUSTRALIA

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Xinyu Liu

Lecturer

Stanford University

UNITED STATES

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Celine Valant

MONASH UNIVERSITY

AUSTRALIA

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Matthew J. Belousoff

MONASH UNIVERSITY

AUSTRALIA

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Andrew B. Tobin

UNITED KINGDOM

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Ziqiu Tong

MONASH UNIVERSITY

AUSTRALIA

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Patrick M. Sexton

Research Interests

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Articles (15)

Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein

Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3

Impact of secretin receptor homo-dimerization on natural ligand binding

Porous Silicon Microparticles Enable Sustained Release of GLP‐1R Agonist Peptides for the Treatment of Type 2 Diabetes

Development of a Novel Assay for Direct Assessment of Selective Amylin Receptor Activation Reveals Novel Differences in Behavior of Selective and Nonselective Peptide Agonists

Structural basis of efficacy-driven ligand selectivity at GPCRs

Author Correction: Structural basis of efficacy-driven ligand selectivity at GPCRs

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR

New Insights into the Structure and Function of Class B1 GPCRs

Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits

M 1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease

Secretin amino-terminal structure-activity relationships and complementary mutagenesis at the site of docking to the secretin receptor

Structural and functional diversity among agonist-bound states of the GLP-1 receptor

Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM

Implications of ligand-receptor binding kinetics on GLP-1R signalling

Collaborators (13)

Emma van der Westhuizen

David M. Thal

Giuseppe Deganutti

Mario Rossi

Shailesh N. Mistry

Radostin Danev

Arthur Christopoulos

Christopher J. Langmead

Xinyu Liu

Celine Valant

Matthew J. Belousoff

Andrew B. Tobin

Ziqiu Tong

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