Peter Cossar

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Eindhoven University of Technology

Netherlands

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Recent Grants

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International Network of Excellence in Science Technology

Open Date: 2017-06-01

Close Date: 2022-05-31

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Year:

2021

Year:

2021

Collaborators (7)

Adam McCluskey

Newcastle University

AUSTRALIA

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Michelle R. Arkin

University of California

UNITED STATES

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Luc Brunsveld

Prof. at Eindhoven University of Technology

Eindhoven University of Technology

NETHERLANDS

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Christian Ottmann

NETHERLANDS

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Auke Koops

Eindhoven University of Technology

NETHERLANDS

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Aneika C. Leney

University of Birmingham

UNITED KINGDOM

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Tomas Obsil

Head of department/Professor

Charles University, Faculty of Science

CZECH REPUBLIC

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Peter Cossar

Research Interests

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Recent Grants

Articles (10)

Molecular basis and dual ligand regulation of tetrameric Estrogen Receptor α/14-3-3ζ protein complex

Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein–Protein Interaction as a Molecular Glue Drug Discovery Approach

Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry

Functional mapping of the 14-3-3 hub protein as a guide to design 14-3-3 molecular glues

Fragment-based exploration of the 14-3-3/Amot-p130 interface

Cytotoxic 1,2,3-Triazoles as Potential Leads Targeting the S100A2-p53 Complex: Synthesis and Cytotoxicity.

Targeting the S100A2-p53 Interaction with a Series of 3,5-Bis(trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity

An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB-Utilizing a Reversible Covalent Tethering Approach.

Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.

Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt.

Collaborators (7)

Adam McCluskey

Michelle R. Arkin

Luc Brunsveld

Christian Ottmann

Auke Koops

Aneika C. Leney

Tomas Obsil

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