Rachel Clare

Academic, Senior Lecturer in Biochemistry

Edge Hill University

United Kingdom

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Dr. Rachel Clare is a Senior Lecturer in Biochemistry at Edge Hill University, located in the UK. Her research primarily focuses on snakebite envenoming treatments, including the development of innovative therapies and drug discovery methods. Recent publications highlight her work on the pharmacological stability of African polyvalent antivenom and the use of Galleria mellonella larvae as a model for studying snakebite envenoming.

Articles (10)

Year:

2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2022

Year:

2021

Collaborators (9)

Steve Ward

Walter Myers Professor of Parasitology

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Andreas Hougaard Laustsen

Technical University of Denmark

DENMARK

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Steven Hall

Lancaster University

UNITED KINGDOM

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Line Ledsgaard

Technical University of Denmark

DENMARK

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Guillaume Hoffmann

INSERM

FRANCE

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Nicholas Casewell

Professor of Tropical Disease Biology

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Stefanie Menzies

University of Lancaster

UNITED KINGDOM

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Dr. Cassandra Modahl

Lecturer

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Mark Taylor

Head of Centre for Neglected Tropical Diseases

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Rachel Clare

Research Interests

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Articles (10)

Development of an oral regimen of unithiol for the treatment of snakebite envenoming

Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host

African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages

Intraspecific venom variation in the medically important puff adder ( Bitis arietans ): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

Development of Galleria mellonella (wax moth) larvae as a model for snakebite envenoming

Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform

Snakebite drug discovery

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules

In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus

Development of Pyrazolopyrimidine Anti-<i>Wolbachia</i> Agents for the Treatment of Filariasis.

Collaborators (9)

Steve Ward

Andreas Hougaard Laustsen

Steven Hall

Line Ledsgaard

Guillaume Hoffmann

Nicholas Casewell

Stefanie Menzies

Dr. Cassandra Modahl

Mark Taylor

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