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Line Ledsgaard

Technical University of Denmark

Denmark

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Research Interests

Immunology

90%

Biochemistry

50%

Antibodies

90%

Toxinology

50%

Bioanalytical Chemistry

50%

Assay Development

30%

Antibody Therapy

30%

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Articles16

Section-level genome sequencing and comparative genomics of Aspergillus sections Cavernicolus and Usti

Article Link

Year:

2025

Genomic Analysis of <i>Aspergillus</i> Section <i>Terrei</i> Reveals a High Potential in Secondary Metabolite Production and Plant Biomass Degradation

Article Link

Year:

2024

Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling

Article Link

Year:

2024

Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper

Article Link

Year:

2024

Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy

Article Link

Year:

2023

Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

Article Link

Year:

2023

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules

Article Link

Year:

2023

Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

Article Link

Year:

2023

In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom

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Year:

2022

Orally active bivalent VHH construct prevents proliferation of F4+ enterotoxigenic Escherichia coli in weaned piglets

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Year:

2022

Synthetic antibodies block receptor binding and current‐inhibiting effects of α‐cobratoxin from Naja kaouthia

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Year:

2022

Advances in antibody phage display technology

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Year:

2022

Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses

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Year:

2021

An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies

Article Link

Year:

2020

Discovery of a Recombinant Human Monoclonal Immunoglobulin G Antibody Against α-Latrotoxin From the Mediterranean Black Widow Spider (Latrodectus tredecimguttatus)

Article Link

Year:

2020

Unity Makes Strength: Exploring Intraspecies and Interspecies Toxin Synergism between Phospholipases A2 and Cytotoxins

Article Link

Year:

2020

Collaborators28

Aneesh Karatt Vellatt

Chief Scientific Officer

UNITED KINGDOM

Berthe Katrine Fiil

Assistant Prof

University of Copenhagen

DENMARK

Chiara Francavilla

The University of Manchester

UNITED KINGDOM

Tulika Tulika

Technical University of Denmark

DENMARK

Andreas Hougaard Laustsen

Technical University of Denmark

DENMARK

Miia Mäkelä

University of Helsinki

FINLAND

Bjørn Gunnar Voldborg

Technical University of Denmark

DENMARK

Anne Ljungars

Technical University of Denmark

DENMARK

Uffe Hasbro Mortensen

Professor

Technical University of Denmark

DENMARK

Susanne Brix Pedersen

Technical University of Denmark

DENMARK

Timothy P. Jenkins

Technical University of Denmark

DENMARK

Jens Frisvad

Technical University of Denmark

DENMARK

Julian Harrison

ETH Zürich

SWITZERLAND

Rachel Clare

Academic, Senior Lecturer in Biochemistry

Edge Hill University

UNITED KINGDOM

Igor Grigoriev

Adjunct Professor

University of California, Berkeley

UNITED STATES

Selma Belfakir

Technical University of Denmark

DENMARK

Nicholas Casewell

Professor of Tropical Disease Biology

Liverpool School of Tropical Medicine

UNITED KINGDOM

Lars Jelsbak

Professor at Technical University of Denmark

Technical University of Denmark

DENMARK

Esperanza Rivera-de-Torre

Technical University of Denmark

DENMARK

Jonas Arnold Jürgensen

Technical University of Denmark

DENMARK

Tammi Camilla Vesth

Technical University of Denmark

DENMARK

Christoffer Vinther Sørensen

Technical University of Denmark

DENMARK

Jens Preben Morth

Technical University of Denmark

DENMARK

Anna Christina Adams

Group head pharmaceutical biotechnology

RWTH Aachen University

GERMANY

Thomas Ostenfeld Larsen

Technical University of Denmark

DENMARK

Astrid Mueller

NETHERLANDS

Shirin Ahmadi

Technical University of Denmark

DENMARK

Markus-Frederik Bohn

Associate Professor

Danmarks Tekniske Universitet

DENMARK

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