Meet ApplyKite Twin, the application assistant that learns with you

Meet your Twin, it learns with you

Your Twin learns with you

Launch week codes:30% off annual Pro20% off monthly Pro

Ends in00h00m00s

Sarka Lehtonen

Has grant

Associate Professor (tenure track)

University of Eastern Finland

Finland

Research Interests

Explore related searches

Professors in Finland Professors in Tissue Engineering Tissue Engineering professors in Finland

Recent Grants

Grant: Close

Brain-on-a-chip

Open Date: 2022-04-01

Close Date: 2022-11-01

Grant: Close

Metabolic profiling of human microglia from LRRK2 Parkinson's disease patients

Open Date: 2022-01-01

Close Date: 2022-12-01

Grant: Close

Microglia-driven pathology in PD

Open Date: 2021-04-01

Close Date: 2024-03-01

Grant: Close

Molecular crosstalk between astrocytes and microglia in Parkinson`s disease

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Towards novel therapeutic strategies in schizophrenia

Open Date: 2021-01-01

Close Date: 2021-12-01

Articles (20)

Year:

2026

Year:

2026

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Collaborators (21)

Pinja Kettunen

University of Helsinki

FINLAND

View details

Katharina Günther

University of Innsbruck

AUSTRIA

View details

Samudyata Samudyata

Assistant Professor

Karolinska Institutet

SWEDEN

View details

Martina Schmidt

Scientific Staff, Professor, Hoogleraar

University of Groningen

NETHERLANDS

View details

Marja Koskuvi

University of Helsinki

FINLAND

View details

Katrina Albert

University of Cambridge

UNITED KINGDOM

View details

Jussi Kukkonen

Professor

University of Eastern Finland

FINLAND

View details

Lesley Cheng

La Trobe University

AUSTRALIA

View details

Iiris Hovatta

University of Helsinki

FINLAND

View details

Jari Koistinaho

University of Helsinki

FINLAND

View details

Angeliki Spathopoulou

Senior scientist

University of Innsbruck

AUSTRIA

View details

Sophie Erhardt

Chair, Department of Physiology and Pharmacology

Karolinska Institutet

SWEDEN

View details

Sami Heikkinen

Research Director

University of Eastern Finland

FINLAND

View details

Tristen Hewitt

University of Helsinki

FINLAND

View details

Jari Tiihonen

Karolinska Institutet

SWEDEN

View details

Ilya Belevich

University of Helsinki

FINLAND

View details

Olli Pietilainen

University of Helsinki

FINLAND

View details

Alfredo Ramirez

University of Texas Health Science Center at San Antonio

UNITED STATES

View details

Amalia Dolga

Scientific Staff, Professor, Hoogleraar

University of Groningen

NETHERLANDS

View details

Polina Ilina

University of Helsinki

FINLAND

View details

Arto Koistinen

Deputy Head of Department (research)

University of Eastern Finland

FINLAND

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Sarka Lehtonen

Research Interests

Explore related searches

Recent Grants

Articles (20)

C9orf72-associated and sporadic FTD patient iPSC-microglia show differences in phagocytosis and gene expression

Air-Liquid interface midbrain organoids model the pathological features of Parkinson’s disease

Traffic-related diesel pollution particles impair the lysosomal functions of human iPSC-derived microglia

miRNA profiling of hiPSC-derived neurons from monozygotic twins discordant for schizophrenia

Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype.

Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia.

Human microglia reduce alpha-synuclein aggregation and are neuroprotective in adult mouse brain

Uptake of alpha‐synuclein preformed fibrils is suppressed by inflammation and induces an aberrant phenotype in human microglia

APPswe mutation causes functional deficits in endothelial cells generated by transient ETV2 overexpression in human iPSCs

From inserts to chips: microfluidic culture and 3D astrocyte co-culture drive functional and transcriptomic changes in hiPSC-derived endothelial cells

Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner

Genetic contribution to microglial activation in schizophrenia

Identification of the abnormalities in astrocytic functions as potential drug targets for neurodegenerative disease

Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia

Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling

Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes

Biotransformation of nanoplastics in human plasma and their permeation through a model in vitro blood-brain barrier: An in-depth quantitative analysis

Glial cell transplant for brain diseases: the supportive saviours?

LRRK2 G2019S Mutated iPSC-Derived Endothelial Cells Exhibit Increased α-Synuclein, Mitochondrial Impairment, and Altered Inflammatory Responses

INDUCED PLURIPOTENT STEM CELL-DERIVED MICROGLIA TO STUDY NLRP3 INFLAMMASOME ACTIVATION IN ALZHEIMER'S DISEASE,INDÜKLENMIŞ PLURIPOTENT KÖK HÜCRE KAYNAKLI MIKROGLIA HÜCRELERININ ALZHEIMER HASTALIǦINDA NLRP3 INFLAMAZOM AKTIVASYONU ARAŞTIRMALARINDA KULLANIMI

Collaborators (21)

Pinja Kettunen

Katharina Günther

Samudyata Samudyata

Martina Schmidt

Marja Koskuvi

Katrina Albert

Jussi Kukkonen

Lesley Cheng

Iiris Hovatta

Jari Koistinaho

Angeliki Spathopoulou

Sophie Erhardt

Sami Heikkinen

Tristen Hewitt

Jari Tiihonen

Ilya Belevich

Olli Pietilainen

Alfredo Ramirez

Amalia Dolga

Polina Ilina

Arto Koistinen

Make your next move.