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Sonali Barwe

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Senior Research Scientist; Head, Cancer Modeling Laboratory; Director, Cell Science Core; Co-Director Nemours Summer Undergraduate Research Program; Radiation Safety Officer for Research Delaware Valley; Nemours contact for INBRE Summer Scholars

Nemours Children's Hospital Delaware

United States

Research Interests

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Recent Grants

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Elucidate the functional coupling between beta1-subunit of Na,K-ATPase and NCX1 in cardiac contractility

Open Date: 2010-01-01

Close Date: 2013-12-31

Grant: Close

Immunotherapy options for pediatric acute myeloid leukemia

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Articles (19)

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2026

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Collaborators (6)

Baskar Ramdas

Associate Research Professor

University of Indianapolis

UNITED STATES

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Dirk Heckl

Professor (W3) and Director

Goethe University Frankfurt

GERMANY

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Anilkumar Gopalakrishnapillai

Head, Cancer Stem Cell Laboratory

Nemours Childrens Hospital

UNITED STATES

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Reuben Kapur

Professor

Indiana University School of Medicine

UNITED STATES

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Santhosh Kumar

Assistant Research Professor

Indiana State University

UNITED STATES

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Maegan Capitano

Assistant Professor

Indiana University School of Medicine

UNITED STATES

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Sonali Barwe

Research Interests

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Recent Grants

Articles (19)

DLK1 is a GATA1s-driven dependency and therapeutic target in Down syndrome–associated myeloid leukemia

CONCORDANCE OF A CAPILLARY BLOOD COLLECTION DEVICE FOR IMMUNE SURVEILLANCE IN PEDIATRIC SEPSIS

Mesothelin promotes acute myeloid leukemia progression through LYN-dependent signaling

ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche

Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway

Azacitidine-panobinostat activates NF-kb signaling in the bone marrow microenvironment to chemosensitize KMT2A rearranged pediatric AML

BTK regulates EZH2 stability in myeloid leukemia associated with down syndrome

DYRKIA interacts with EZH2 to regulate transcriptionally active chromatin in myeloid leukemia associated with down syndrome

Mechanism of acquired resistance to histone deacetylase inhibitor, romidepsin, in myeloid leukemia associated with down syndrome

Bone Marrow Microenvironment-Induced Chemoprotection in <i>KMT2A</i> Rearranged Pediatric AML Is Overcome by Azacitidine–Panobinostat Combination

Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts

Mesothelin: An Immunotherapeutic Target beyond Solid Tumors

Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia

Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of <i>GATA1</i> and <i>STAG2</i> Mutations in Induced Pluripotent Stem Cells with Trisomy 21

Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies

Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies

The extracellular matrix: A key player in the pathogenesis of hematologic malignancies.

Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology.

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia.

Collaborators (6)

Baskar Ramdas

Dirk Heckl

Anilkumar Gopalakrishnapillai

Reuben Kapur

Santhosh Kumar

Maegan Capitano

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