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Yitian Zhou

Assistant Professor

Karolinska Institutet

Sweden

Research Interests

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Professors in Sweden Professors in Biostatistics Biostatistics professors in Sweden

Articles (29)

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Collaborators (14)

Erik Eliasson

Professor/Senior Physician

Karolinska Institutet

SWEDEN

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Stefania Koutsilieri

Karolinska Institutet

SWEDEN

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Souren Mkrtchian

Karolinska Institutet

SWEDEN

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Maaike van der Lee

Leiden University Medical Center

NETHERLANDS

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Anne T. Nies

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

GERMANY

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Ming Xiao

KTH Royal Institute of Technology

SWEDEN

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Volker Lauschke

Professor

Karolinska Institutet

SWEDEN

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Matthias Schwab

GERMANY

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Henk-Jan Guchelaar

Leiden University Medical Center

NETHERLANDS

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Gunnar Schulte

Professor

Karolinska Institutet

SWEDEN

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Yi Wang

Zhejiang University

CHINA

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Rossana Roncato

Associate Professor of Pharmacology

University of Udine

ITALY

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Jesse Swen

Full professor of clinical pharmacy, in particular translational pharmacogenetics

Leiden University Medical Center

NETHERLANDS

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Espen Molden

Professor

University of Oslo

NORWAY

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Yitian Zhou

Research Interests

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Articles (29)

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Prediction of drug hypersensitivity by comprehensive modeling of HLA-peptidomes

Feed‐Forward Deep Neural Networks Predict Substrate‐Specific Effects of Transporter Variants to Explain Drug Response Variability

Substrate-specificity of pharmacogenomic variability – clinical relevance and emerging predictive strategies

Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account

Integration of germline pharmacogenomic burden to predict fluoropyrimidine-related toxicity – A secondary analysis of the PREPARE trial

Evaluating the synergistic use of advanced liver models and AI for the prediction of drug-induced liver injury

PharmFreq: a comprehensive atlas of ethnogeographic allelic variation in clinically important pharmacogenes

Molecular docking to investigate HLA-associated idiosyncratic drug reactions

Population-scale variability of the human UDP-glycosyltransferase gene family

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Population-specific variations in <i>KCNH2</i> predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Next-generation sequencing in pharmacogenomics – fit for clinical decision support?

Meta-analysis of the global distribution of clinically relevant <i>CYP2C8</i> alleles and their inferred functional consequences

Pharmacogenomics Beyond Single Common Genetic Variants: The Way Forward

Challenges Related to the Use of Next-Generation Sequencing for the Optimization of Drug Therapy

Cross-Ancestry Genome-Wide Association Study Defines the Extended <i>CYP2D6</i> Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations

A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing

The genetic landscape of major drug metabolizing cytochrome P450 genes—an updated analysis of population-scale sequencing data

Challenges and opportunities associated with rare-variant pharmacogenomics

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients

Computational Tools to Assess the Functional Consequences of Rare and Noncoding Pharmacogenetic Variability

Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation

Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment

Pharmacogenomics in the era of next generation sequencing - from byte to bedside

Collaborators (14)

Erik Eliasson

Stefania Koutsilieri

Souren Mkrtchian

Maaike van der Lee

Anne T. Nies

Ming Xiao

Volker Lauschke

Matthias Schwab

Henk-Jan Guchelaar

Gunnar Schulte

Yi Wang

Rossana Roncato

Jesse Swen

Espen Molden

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