PhD in RNA Dysfunction in Parkinson’s Disease using Single-Cell Omics, CRISPR, and Stem Cell Models University of Oxford in United Kingdom

[Home tuition fees plus a Doctoral Stipend for up to 4 years.] PhD Studentship at the University of Exeter in Editing the Alzheimer’s Epigenome: From Human Brain Variation to Functional Mechanisms . This studentship addresses a major question in Alzheimer’s disease research: which epigenetic changes observed in human brain actually alter gene regulation and contribute to disease biology. The project builds on cell-type-specific epigenomic datasets generated from human post-mortem brain using flu...

The University of Cambridge is recruiting a Postdoctoral Research Associate to join the research group of Professor Rita Horvath at the Department of Clinical Neurosciences and the John Van Geest Brain Repair Centre . This post focuses on the molecular and cellular biology of mitochondrial disease models , with a specific emphasis on ataxia telangiectasia , neurological progression, and treatment response. The project is part of a research grant from the joint call of Action Medical Research and...

Exciting fully funded 4-year PhD opportunity in the UK Human Functional Genomics Initiative , advertised by Professor Laura Andreae (Centre for Developmental Neurobiology, King’s College London) in collaboration with Juan Burrone and Nicholas Clifton at the University of Exeter . The project is titled Cellular phenotypes of in vivo grafted human neurons with autism risk mutations . It sits at the intersection of developmental neuroscience , functional genomics , and neurobiology , with a focus o...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on programmed axon death , SARM1 , NMNAT2 , and protein design . The project focuses on understanding the mechanism of programmed axon death, an intrinsic axonal death pathway implicated in neurodegenerative disease and injury. The work will use rational protein design to create variant forms of SARM1 or hybrid reporter constructs to study activation, stability, enzyme activity, and post-translational modi...

PhD opportunity at the University of Cambridge in preclinical human neural organoid and computational/AI model development . This project sits at the intersection of neuroscience , neural organoids , single-cell transcriptomics , spatial transcriptomics , and computational AI . The aim is to combine patient-specific iPSC-derived human neural organoids with postmortem CNS samples to build large-scale AI frameworks that can identify disease-associated cellular states, molecular biomarkers, and pot...