PhD position in high-throughput chemistry and chemical biology University of Leeds in United Kingdom

University of Bath is recruiting a Postdoctoral Research Associate in an interdisciplinary project focused on mammalian cell biology , molecular biology , chemical biology , and peptide screening . The work will develop innovative intracellular peptide screening technologies to investigate and modulate transcription factor function in living mammalian cells. The post is hosted in Professor Jody Mason's research group at the University of Bath and is funded through a new BBSRC Pioneer Award . The...

PhD Studentship in the Biochemistry and Chemical Biology of the Genome and Epigenome at the University of Cambridge , Department of Chemistry. This funded PhD project is offered in Professor Sir Shankar Balasubramanian’s group and focuses on biochemistry , chemical biology , genomics , molecular biology , biophysics , and structural biology . The research explores fundamental mechanisms of genome function, with a strong emphasis on DNA secondary structures such as G-quadruplexes (G4s) , chromati...

PhD opportunity at the University of St Andrews in the School of Biology / School of Chemistry, working on design, synthesis, and mechanism of action of inhibitors of the human enzyme DNPH1 (2′-deoxynucleoside 5′-phosphate N-hydrolase 1). This project sits at the interface of Biochemistry , Structural Biology , Medicinal Chemistry , Organic Synthesis , and Chemical Biology . DNPH1 is a nucleotide-sanitizing enzyme, and the project aims to design potent and selective inhibitors and elucidate how ...

PhD opportunity in pathological protein assembly in neurodegenerative diseases at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom . The project is centered on the molecular pathology of neurodegeneration, with a focus on amyloid filament formation by disease-associated proteins such as TDP-43 , annexin A11 , and TAF15 . Two PhD project directions are described. One aims to reproduce pathological protein filament structures in vitro using protein biochemist...

Funded PhD project at the University of Edinburgh on peptide-based precision anti-infectives for the prophylaxis and prevention of foodborne listeriosis . The project focuses on Listeria monocytogenes , a major foodborne pathogen, and explores a novel anti-virulence strategy targeting the bacterial regulator PrfA . Building on structural and functional discoveries from the Vázquez-Boland group, the PhD will design, synthesise, and evaluate peptide-based PrfA inhibitors as potential Listeria-targ...