PhD Project: The Fitness Effects of Loss-of-Function Mutations in Bacterial Populations (SWBio DTP) University of Bath in United Kingdom

Funded PhD opportunity at the MRC Laboratory of Medical Sciences (LMS) in London, United Kingdom, on spatial and three-dimensional genome regulation during zygotic genome activation (ZGA) . This project explores how chromatin architecture, promoter-enhancer communication, boundary formation, insulation, and spatially restricted transcriptional states are coordinated as the embryonic genome becomes active. The work sits at the intersection of developmental genomics , chromatin biology , genomics ...

PhD opportunity at The Francis Crick Institute with Dr Ekaterina Osipova on genetic mechanisms of metabolic rate control in birds and mammals . This project focuses on how metabolic rate varies across animals and how genetic elements, genes, and regulatory regions shape those differences. The work combines comparative genomics , evolution , genomics , bioinformatics , molecular genetics , and potentially lab-based validation . The lab uses evolutionary rate-based methods and machine-learning app...

PhD opportunity at the Earlham Institute, Norwich, United Kingdom This funded PhD project is titled A single-cell atlas of the Euglena gracilis cell cycle and is hosted by the Earlham Institute within the Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP). The project focuses on single-cell RNA sequencing , cell cycle biology , genomics , bioinformatics , data analysis , data science , microbiology , and molecular biology . Research focus: Euglena gracilis is a highly unusu...

PhD opportunity at the University of East Anglia in Norwich, United Kingdom, focused on single-cell multi-omics , enhancer biology , and the developmental control of blood and cardiovascular fate . The project investigates how enhancer activity changes as blood, endothelial, and cardiac lineages emerge in the chick embryo. You will combine single-cell RNA-sequencing and ATAC-sequencing to reconstruct gene-regulatory networks, identify candidate enhancers, and study how hematoendothelial progenit...

PhD opportunity at the University of East Anglia in historical genomics, ancient DNA, conservation genetics, bioinformatics, evolution, and population genetics . This project, supervised by Dr Anders Bergström at the School of Biological Sciences , focuses on the declining red squirrel in Britain . The research will investigate how historical population decline, invasive grey squirrels, hunting, deforestation, and past translocations from continental Europe have shaped the genetic make-up, ances...