Publisher
source

Mark Searcey

11 months ago

PhD Studentship: Development of New Antibacterial Compounds Targeting Microbial Resistance University of East Anglia in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Available

Deadline

Expired

Country flag

Country

United Kingdom

University

University of East Anglia

Suggested positions

Publisher
source

Coventry University

Country flag

United Kingdom

PhD opportunity in molecular characterisation of the protein S-acylation machinery at Coventry University within the Centre for Discoveries in Life Sciences and the Midlands Integrative Biosciences Training Partnership (MIBTP) . This funded PhD project investigates protein S-acylation (palmitoylation) , a reversible post-translational modification that regulates protein localisation, stability, trafficking, and activity. The project aims to define the molecular interactions between the S-acylati...

Cell Biology
Molecular Biology
Chemistry
+9 more

2 weeks ago

Publisher
source

MRC Laboratory of Medical Sciences

Country flag

United Kingdom

Funded PhD project in telomere biology , cancer biology , peptide design , protein biochemistry , molecular biology , cell biology , and synthetic/pharmaceutical chemistry at the MRC Laboratory of Medical Sciences and Imperial College London in London, United Kingdom . The project asks how cells replicate chromosome ends while preserving telomere protection. You will study the shelterin complex, TRF2 interactions, and the origin recognition complex (ORC), with a focus on how disrupting these int...

Cell Biology
Molecular Biology
Chemistry
+6 more

2 weeks ago

Publisher
source

Jody Mason

University of Bath

Country flag

United Kingdom

University of Bath is recruiting a Postdoctoral Research Associate in an interdisciplinary project focused on mammalian cell biology , molecular biology , chemical biology , and peptide screening . The work will develop innovative intracellular peptide screening technologies to investigate and modulate transcription factor function in living mammalian cells. The post is hosted in Professor Jody Mason's research group at the University of Bath and is funded through a new BBSRC Pioneer Award . The...

Biochemistry
Molecular Biology
Chemistry
+3 more

New Today

Publisher
source

The Francis Crick Institute

Country flag

United Kingdom

Funded PhD project at The Francis Crick Institute in London, United Kingdom, with Dr Frank Uhlmann and the Chromosome Segregation Laboratory. The project, Chromosome Organisation by Dynamic Cohesin Complexes , focuses on chromosome organisation , cohesin , chromatin loops , topologically associating domains , and the broader mechanisms of genome organisation and chromosome segregation . The lab studies how Structural Maintenance of Chromosome (SMC) complexes support sister chromatid cohesion, ch...

Cell Biology
Molecular Biology
Biophysics
+4 more

3 weeks ago

Publisher
source

MRC Laboratory of Molecular Biology

Country flag

United Kingdom

📢 The MRC Laboratory of Molecular Biology (LMB) is inviting prospective PhD students to explore its doctoral opportunities in molecular biology and related biological sciences. Applications are now open for October 2027 entry. The post does not specify funding, supervisor names, or detailed eligibility criteria, but it clearly targets PhD applicants interested in research training at a leading molecular biology institute. Interested candidates should review the linked opportunity page for the fu...

Molecular Biology
Biology
Medical Science
+1 more

1 week ago

Keywords

Cell Biology
Molecular Biology
Chemistry
Biology
Health Science
Antibiotic Resistance
Chemical Synthesis
Chemical Biology
Bacterial Genetics
Bioassay
Hospital Pharmacy
Antibacterial Activity
Bioscience
Computer-aided Drug Design

About this position

[Fully funded 4-year PhD CASE studentship with Inspiralis Limited, including payment of tuition fees, annual stipend of £20,780 (2025/6 rate), and a Research Training Support Grant of £5,000 per year.] This fully funded PhD studentship at the University of East Anglia focuses on the development of new antibacterial compounds to combat the growing threat of antibiotic resistance. Supervised by Professor Mark Searcey and Dr Andrew Gates, the project aims to identify and target unique DNA structures in bacteria, specifically the four way junction (4WJ) formed by inverted repeats in the bacterial genome. The research will involve a multidisciplinary approach, combining biophysical and biochemical assays to study these DNA structures, and employing both solid and solution phase synthesis to create novel molecules that can bind and potentially stabilize or disrupt the 4WJ formation.

The effects of these compounds on bacteria will be evaluated using advanced methods developed at UEA. The studentship is part of the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP), which offers a comprehensive training programme and a vibrant research community. All NRPDTP students undertake a three-month professional internship placement (PIPS) to gain valuable work experience and enhance professional development.

The project is a CASE studentship in partnership with Inspiralis Limited, providing full financial support including tuition fees, a generous annual stipend of £20,780, and a research training support grant of £5,000 per year. Applicants should hold or expect to obtain a first class or 2:1 Honours degree in Chemistry, Biochemistry, Pharmacology, or a related discipline, and must meet the English language requirements (IELTS 6.5 overall, 6.0 in each category).

The position is full-time, starting in October 2026, with interviews for shortlisted candidates scheduled for February 2026. For further information on eligibility and application procedures, candidates are encouraged to visit the NRPDTP website or contact the supervisors directly.

Funding details

Available

What's required

Applicants must have, or expect to obtain, a first class or 2:1 (upper second class) Honours degree or equivalent in Chemistry, Biochemistry, Pharmacology, or a related area. English language proficiency is required: IELTS 6.5 overall, with at least 6.0 in each category. The position is full-time and starts in October 2026.

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts and confirm requirements with the university.

Professors

Professor at University of East Anglia

University Name
Country flag

United Kingdom

Research Interests

Pharmacology

Pharmaceutical Chemistry

Ligand Design

Peptide Chemistry

Chemical Biology

Dr at University of East Anglia

University Name
Country flag

United Kingdom

Research Interests

Cell Biology

Hospital Pharmacy

Chemical Biology

Bioassay

Health Science