PhD Studentship: Elucidating E. Coli-microbiome Crosstalk in Crohn’s Disease University of East Anglia in United Kingdom

PhD opportunity in immunology and molecular biology at the Medical Research Council (Cambridge), Laboratory of Molecular Biology. The project, supervised by Dr Patrycja Kozic, asks whether perforin-2 (Mpeg1) forms pores in two orientations and how this ancient MACPF/CDC family protein is regulated during immune responses. The research focuses on perforin-2 function in dendritic cells and macrophages, especially its roles in attacking intravacuolar pathogens and enabling cytosolic antigen deliver...

PhD opportunity at Quadram Institute Bioscience in Norwich, United Kingdom, within the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP). The project is titled Role of non-canonical autophagy in liver lipid metabolism in response to unhealthy diets and sits at the intersection of autophagy, liver lipid metabolism, fatty liver disease, obesity, hepatocyte biology, LC3-associated phagocytosis, cell biology, molecular biology, immunology , and translational biomedical research....

PhD Studentship: The Hidden Immune System of Fungi—Uncovering the Roles of NLR Genes The University of Birmingham is offering a PhD studentship in fungal immunology and molecular microbiology, based in Birmingham, United Kingdom. The project investigates how nucleotide-binding and leucine-rich repeat (NLR) genes contribute to the cryptic immune system of fungi. Using the genetically tractable wheat pathogen Zymoseptoria tritici , which contains 20 NLRs, the research will examine fungal-bacterial...

PhD opportunity in Drosophila morphogenesis, cell contractility, and developmental biology at the University of St Andrews. This EASTBIO-funded project investigates the mechanisms underlying pulsed contractions during morphogenesis, with a focus on how rhythmic cytoskeletal contractility drives apical constriction and tissue shaping in Drosophila larval epithelial cells. The project combines cell biology , genetics , and molecular biology with advanced imaging and manipulation approaches. You wi...

The Babraham Institute is recruiting a Postdoctoral Research Scientist to study the role of extracellular proteostasis in healthy ageing and host defence against pathogens. The project addresses mechanisms that maintain protein quality outside cells and prevent protein aggregation, a process associated with age-related functional decline and diseases such as Alzheimer’s disease. The successful researcher will join the David group within the Institute’s Signalling Programme, a collaborative resea...