Postdoctoral Opportunity in Cryo-EM Structures and Mechanisms of Bacterial Secretion Systems Imperial College London in United Kingdom

PhD opportunity at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom on structural and cellular approaches to understand microtubule motors . This project sits at the intersection of cell biology , molecular biology , and structural biology , with a strong focus on microtubule motors such as dynein and kinesin . The research asks how motors are linked to cargos and coordinated to deliver organelles, RNAs, and proteins to the correct destination, especially...

PhD opportunity in DNA repair at stalled replication forks at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom . The project focuses on DNA repair , replication stress , and the Fanconi Anaemia (FA) pathway , with particular attention to how cells respond to DNA crosslinks and stalled replication forks. The research aims to understand the molecular mechanisms of crosslink repair and the role of the FANCD2-FANCI heterodimer and FA core complex in mai...

The University of Bristol is accepting applications for a funded PhD investigating how free fatty acids regulate beta-coronavirus infection. Co-supervised by Christiane Berger-Schaffitzel, Andrew Davidson, Harriet Mears and Paul Verkade, the project will examine how free fatty acids influence coronavirus infection, replication and evolution. It builds on the discovery of a conserved fatty acid-binding pocket in the coronavirus spike protein. The research combines structural biology, electron cry...

PhD opportunity in Structural Biology , Molecular Biology , Biochemistry , and Human Genetics focused on the human replisome and the mechanisms of DNA replication. The project is hosted by the Medical Research Council (Cambridge) Laboratory of Molecular Biology in the United Kingdom and is supervised by Dr J Yeeles . The lab studies how the human replication machinery is assembled, how it functions during normal DNA duplication, and how it responds to obstacles such as DNA damage and protein bar...

PhD opportunity in AMPA receptor structure and function at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom . This project sits at the intersection of neuroscience , molecular biology , and structural biology , focusing on how AMPA glutamate receptors (AMPA-Rs) and their auxiliary proteins shape excitatory synaptic transmission, plasticity, and information storage in the brain. The lab aims to decode AMPAR signalling complexity from atomic structure...