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Jutte J.C. de Vries

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Associate Professor in Clinical Virology (MD, PhD)

Leiden University Medical Center

Netherlands

Research Interests

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About

Jutte J.C. de Vries is an Associate Professor of Clinical Virology at Leiden University Medical Center in the Netherlands. His research focuses on clinical virology, particularly in the areas of intra-host evolution of viruses, immune responses to viral infections, and innovative diagnostic approaches in metagenomics. His recent publications include studies on SARS-CoV-2, parvovirus B19 in immunocompromised patients, and the benchmarking of viral sequencing methods.

Recent Grants

Grant: Close

CLEAR Trial: Achieving viral clearance in immunocompromised longterm shedders of SARS-CoV 2 – an open-label randomized trial

Open Date: 2026-01-01

Close Date:

Grant: Open

HaDEA RANGER: RApid Next Generation Sequencing for Effective Medical Response

Open Date: 2025-01-01

Close Date: 2029-01-01

Grant: Open

MUSICC: MUcoSal Immunity in human Coronavirus Challenge

Open Date: 2024-01-01

Close Date: 2028-01-01

Grant: Close

NCOH Pandemic Preparedness Kickstarter

Open Date: 2023-09-01

Close Date: 2024-09-01

Grant: Close

BREAK COVID: COVID-19 breakthrough infections and correlates of protection

Open Date: 2023-02-01

Close Date: 2023-12-01

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Collaborators (31)

Meta Roestenberg

Helmholtz Centre for Infection Research

NETHERLANDS

Jutte J.C. de Vries

Research Interests

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About

Recent Grants

Articles (23)

Probe-based metagenomic sentinel surveillance of viral respiratory infections in primary care: a prospective, national, pilot study

The impact of clinical metagenomic testing on patient management: facts versus fantasy

The Regulatory Landscape for Clinical Metagenomic Testing.

Intra-Host Evolution During Relapsing Parvovirus B19 Infection in Immunocompromised Patients

Bivalent mRNA vaccine booster enhances immunity against XBB.1.5 more effectively than breakthrough infection in K18-hACE2 mice

Metagenomic and transcriptomic investigation of pediatric acute liver failure cases reveals a common pathway predominated by monocytes

No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE Trials

Comparison of the performance of two targeted metagenomic virus capture probe-based methods using reference control materials and clinical samples

Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics

Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.

Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease.

A Targeted LC-MRM3 Proteomic Approach for the Diagnosis of SARS-CoV-2 Infection in Nasopharyngeal Swabs

Establishing immunogenicity and safety of needle-free intradermal delivery by nanoporous ceramic skin patch of mRNA SARS-CoV-2 vaccine as a revaccination strategy in healthy volunteers

A comparison of five Illumina, Ion Torrent, and nanopore sequencing technology-based approaches for whole genome sequencing of SARS-CoV-2

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.

Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort

Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

The multidimensional nature of metagenomics drives interdisciplinary diagnostics

Viral metagenomic sequencing in the diagnosis of meningoencephalitis: a review of technical advances and diagnostic yield

Viral metagenomic sequencing in a cohort of international travellers returning with febrile illness

Collaborators (31)

Meta Roestenberg

Anna H.E. Roukens

Manfred Wuhrer

Annemieke Geluk

Cornelis Hokke

Michael Huber

Navid Sadri

Aloysius Kroes

Anne van der Does

Simon Jochems

Jacques J.M. van Dongen

Adam Meijer

Yassene Mohammed

Tom H. M. Ottenhoff

Marjolein Kikkert

Krista van Meijgaarden

Nicolas Drouin

Michael Wilson

Jelle J Goeman

Leendert Trouw

Ian Pichler

Frank Staal

Simone A Joosten

Chunkyu Ko

Andrés Antón Pagarolas

Bernard van den Berg

Huldrych Günthard

Eric Snijder

Tomas Mikal Eagan

Pieter Hiemstra

Hailiang Mei

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