Annemieke Geluk

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Professor Immunodiagnostic of Mycobacterial Diseases

Leiden University Medical Center

Netherlands

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About

Professor Annemieke Geluk is an esteemed faculty member at the Leiden University Medical Center in the Netherlands. Her research focuses on immunodiagnostic methods for mycobacterial diseases, with recent publications addressing issues such as leprosy incidence, immune responses, and tuberculosis diagnostics. She is dedicated to advancing the understanding of mycobacterial control and treatment challenges through innovative research and comprehensive analyses.

Recent Grants

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Point-of-care immunodiagnostic tests for detection of leprosy and detection of Mycobacterium leprae infection in high and low endemic areas in the South American Amazon.

Open Date: 2021-05-01

Close Date: 2025-04-01

Grant: Close

TriageTB: Field evaluation of a point of care triage test for active tuberculosis

Open Date: 2020-02-01

Close Date: 2024-01-01

Grant: Close

EnDxTB: Evaluation of New Diagnostics for Incident, Active and Recurrent TB

Open Date: 2020-01-01

Close Date: 2024-01-01

Grant: Close

Monitoring the effect of prophylactic interventions in contacts of leprosy patients including field-application of a novel immunodiagnostic test in Bangladesh

Open Date: 2019-04-01

Close Date: 2022-03-01

Grant: Close

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

Open Date: 2018-09-01

Close Date: 2023-03-01

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UNITED KINGDOM

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Leendert Trouw

Professor

Leiden University Medical Center

NETHERLANDS

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Jutte J.C. de Vries

Associate Professor (Clinical Virology)

Leiden University Medical Center

NETHERLANDS

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Frank Staal

Professor

Leiden University Medical Center

NETHERLANDS

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Simone A Joosten

Associate Professor

Leiden University Medical Center

NETHERLANDS

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Jan Hendrik Richardus

Erasmus University Rotterdam

NETHERLANDS

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Bernard van den Berg

Assistant professor

Leiden University Medical Center

NETHERLANDS

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Eric Snijder

Professor of Molecular Virology

Leiden University

NETHERLANDS

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Annemieke Geluk

Research Interests

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Recent Grants

Articles (20)

Risk factors and leprosy incidence among contacts in Bangladesh: A multilevel analysis

Advancing Mycobacterium leprae transmission research: Insights from the R2STOP fund

Integrative immune analysis in patients with leprosy reveals host factors associated with mycobacterial control

Anti-phenolic glycolipid antibodies in Mycobacterium bovis infected cattle

Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study

Family-based genetics identifies association of CUBN, IL1RL1 and PRKN variants with leprosy in Bangladesh

Challenges associated with dapsone for leprosy treatment in Indonesia - urgent need for access to alternative antimicrobial drugs

Exploration of the plasma proteomic profile of patients at risk of thromboembolic events

Intradermal versus subcutaneous immunization: Effects of administration route using a lipid-PLGA hybrid nanoparticle tuberculosis vaccine

Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.

Field evaluation of a point-of-care triage test for active tuberculosis (TriageTB)

The course of cytokine and chemokine gene expression in clinically suspect arthralgia patients during progression to inflammatory arthritis

Protocol, rationale and design of BE-PEOPLE (Bedaquiline enhanced exposure prophylaxis for LEprosy in the Comoros): a cluster randomized trial on effectiveness of rifampicin and bedaquiline as post-exposure prophylaxis of leprosy contacts

Mycobacterium leprae and host immune transcriptomic signatures for reactional states in leprosy

T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results.

Protein Levels of Pro-Inflammatory Cytokines and Chemokines as Biomarkers of <i>Mycobacterium bovis</i> Infection and BCG Vaccination in Cattle.

Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis.

Collaborators (13)

Anna H.E. Roukens

Cornelis Hokke

Anne van der Does

Simon Jochems

Ellis Niemantsverdriet

Jackie Cliff

Leendert Trouw

Jutte J.C. de Vries

Frank Staal

Simone A Joosten

Jan Hendrik Richardus

Bernard van den Berg

Eric Snijder

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