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Cornelis Hokke

Professor

Leiden University Medical Center

Netherlands

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Research Interests

Immunology

90%

Microbiology

60%

Glycobiology

70%

Antibodies

60%

Parasitology

40%

Immune Response

40%

Antimicrobial Peptide

40%

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Articles22

Systems analysis unravels a common rural-urban gradient in immunological profile, function and metabolic dependencies

Article Link

Year:

2025

Extracellular Vesicles From Schistosoma mansoni Adult Worms Stimulate IL‐10 Release by B Cells

Article Link

Year:

2025

High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2

Article Link

Year:

2024

Validation of artificial intelligence-based digital microscopy for automated detection of Schistosoma haematobium eggs in urine in Gabon

Article Link

Year:

2024

A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of GlcNAc

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Year:

2023

A review on innovative optical devices for the diagnosis of human soil-transmitted helminthiasis and schistosomiasis: from research and development to commercialization

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Year:

2023

Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity

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Year:

2023

Daily disease severity in patients with COVID-19 admitted to the hospital: The SCODA (severity of coronavirus disease assessment) score

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Year:

2023

Life stage-specific glycosylation of extracellular vesicles from Schistosoma mansoni schistosomula and adult worms drives differential interaction with C-type lectin receptors DC-SIGN and MGL

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Year:

2023

Plant-based production of a protective vaccine antigen against the bovine parasitic nematode Ostertagia ostertagi

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Year:

2023

Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study

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Year:

2023

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.

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Year:

2022

Mass Spectrometric and Glycan Microarray–Based Characterization of the Filarial Nematode Brugia malayi Glycome Reveals Anionic and Zwitterionic Glycan Antigens

Article Link

Year:

2022

Optimized Protocol for the Isolation of Extracellular Vesicles from the Parasitic Worm Schistosoma mansoni with Improved Purity, Concentration, and Yield

Article Link

Year:

2022

Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A

Article Link

Year:

2021

Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A

Article Link

Year:

2021

Cross-reactive carbohydrate determinant-specific IgE obscures true atopy and exhibits alpha-1,3-fucose epitope-specific inverse associations with asthma

Article Link

Year:

2021

Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid

Article Link

Year:

2021

Functional characterization of Schistosoma mansoni fucosyltransferases in Nicotiana benthamiana plants (vol 10, 18528, 2020)

Article Link

Year:

2021

Generation of glucosylated sn-1-glycerolphosphate teichoic acids: glycerol stereochemistry affects synthesis and antibody interaction

Article Link

Year:

2021

Potential of antibody test using Schistosoma mansoni recombinant serpin and RP26 to detect light-intensity infections in endemic areas

Article Link

Year:

2021

Specificity of the Point-of-Care Urine Strip Test for Schistosoma Circulating Cathodic Antigen (POC-CCA) Tested in Non-Endemic Pregnant Women and Young Children

Article Link

Year:

2021

Collaborators18

Per-Johan Jakobson

Professor

Karolinska Institutet

SWEDEN

Anna H.E. Roukens

Leiden University Medical Center

NETHERLANDS

Manfred Wuhrer

Head Center for Proteomics and Metabolomics, Prof. Proteomics and Glycomics

Leiden University Medical Center

NETHERLANDS

Annemieke Geluk

Professor Immunodiagnostic of Mycobacterial Diseases

Leiden University Medical Center

NETHERLANDS

Esther N. M. Nolte-‘t Hoen

Utrecht University

NETHERLANDS

Leendert Trouw

Professor

Leiden University Medical Center

NETHERLANDS

Fabrizio Chiodo

Research Assistant Professor

National Research Council

ITALY

Maria Yazdanbakhsh

Head of Department of Parasitology

Leiden University Medical Center

NETHERLANDS

Hermelijn H. Smits

NETHERLANDS

Geert Roozen

Leiden University Medical Center

NETHERLANDS

Jutte J.C. de Vries

Associate Professor (Clinical Virology)

Leiden University Medical Center

NETHERLANDS

Frank Staal

professor

Leiden University Medical Center

NETHERLANDS

Simone A Joosten

Associate Professor

Leiden University Medical Center

NETHERLANDS

Roman Koning

Assistant Professor

Leiden University Medical Center

NETHERLANDS

Ramaswamy Kalyanasundaram

University of Illinois at Urbana-Champaign

UNITED STATES

Susan Kloet

Assistant Professor - Head, Leiden Genome Technology Center

Leiden University Medical Center

NETHERLANDS

FEDERICA COMPOSTELLA

Associate Professor

Università degli Studi di Torino

ITALY

Emma Houlder

Leiden University Medical Center

NETHERLANDS

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