Cornelis Hokke

Professor

Leiden University Medical Center

Netherlands

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Professor Cornelis Hokke is a faculty member at Leiden University Medical Center in the Netherlands. His research primarily focuses on immunological responses related to schistosomiasis, including the role of extracellular vesicles and glycosylation in immune modulation. He has contributed significantly to the development of diagnostic tools for various diseases, including tuberculosis and COVID-19, through innovative methodologies and artificial intelligence applications.

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Collaborators (18)

Per-Johan Jakobson

Professor

Karolinska Institutet

SWEDEN

Cornelis Hokke

Research Interests

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Articles (22)

Systems analysis unravels a common rural-urban gradient in immunological profile, function and metabolic dependencies

Extracellular Vesicles From Schistosoma mansoni Adult Worms Stimulate IL‐10 Release by B Cells

High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2

Validation of artificial intelligence-based digital microscopy for automated detection of Schistosoma haematobium eggs in urine in Gabon

A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of GlcNAc

A review on innovative optical devices for the diagnosis of human soil-transmitted helminthiasis and schistosomiasis: from research and development to commercialization

Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity

Daily disease severity in patients with COVID-19 admitted to the hospital: The SCODA (severity of coronavirus disease assessment) score

Life stage-specific glycosylation of extracellular vesicles from Schistosoma mansoni schistosomula and adult worms drives differential interaction with C-type lectin receptors DC-SIGN and MGL

Plant-based production of a protective vaccine antigen against the bovine parasitic nematode Ostertagia ostertagi

Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.

Mass Spectrometric and Glycan Microarray–Based Characterization of the Filarial Nematode Brugia malayi Glycome Reveals Anionic and Zwitterionic Glycan Antigens

Optimized Protocol for the Isolation of Extracellular Vesicles from the Parasitic Worm Schistosoma mansoni with Improved Purity, Concentration, and Yield

Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A

Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A

Cross-reactive carbohydrate determinant-specific IgE obscures true atopy and exhibits alpha-1,3-fucose epitope-specific inverse associations with asthma

Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid

Functional characterization of Schistosoma mansoni fucosyltransferases in Nicotiana benthamiana plants (vol 10, 18528, 2020)

Generation of glucosylated sn-1-glycerolphosphate teichoic acids: glycerol stereochemistry affects synthesis and antibody interaction

Potential of antibody test using Schistosoma mansoni recombinant serpin and RP26 to detect light-intensity infections in endemic areas

Specificity of the Point-of-Care Urine Strip Test for Schistosoma Circulating Cathodic Antigen (POC-CCA) Tested in Non-Endemic Pregnant Women and Young Children

Collaborators (18)

Per-Johan Jakobson

Anna H.E. Roukens

Manfred Wuhrer

Annemieke Geluk

Esther N. M. Nolte-‘t Hoen

Leendert Trouw

Fabrizio Chiodo

Maria Yazdanbakhsh

Hermelijn H. Smits

Geert Roozen

Jutte J.C. de Vries

Frank Staal

Simone A Joosten

Roman Koning

Ramaswamy Kalyanasundaram

Susan Kloet

FEDERICA COMPOSTELLA

Emma Houlder

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