Daniel Levey

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Assistant Professor

Yale University

United States

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Daniel Levey is an Assistant Professor at Yale University in the United States. His research focuses on epigenetics, genomic profiling, and the genetic architecture of mental health disorders, with recent articles addressing topics such as substance dependence, depression, and Alzheimer's disease. His work also explores the intersections of genetic risk and behavioral health, contributing to the understanding of comorbidity patterns and the biological mechanisms underlying psychopathology.

Recent Grants

Grant: Close

Investigating the Genomic Architecture of Anxiety and Overlap with Mental Health Disorders in the Million Veteran Program.

Open Date: 2021-09-01

Close Date: 2026-08-01

Grant: Close

An Investigation of Shared Genetic Risk Factors for Anxiety, Depression and Suicide in the Million Veterans Program.

Open Date: 2020-01-15

Close Date: 2022-01-14

Daniel Levey

Research Interests

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About

Recent Grants

Articles (28)

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses

A contextual genomic perspective on physical activity and its relationship to health, well being and illness

Integrating HiTOP and RDoC frameworks Part I: Genetic architecture of externalizing and internalizing psychopathology

Integrating HiTOP and RDoC frameworks part II: shared and distinct biological mechanisms of externalizing and internalizing psychopathology

Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits

Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders

Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression

A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD

Examining Methylation at the Intersection of Genetic Risk To Alzheimer’s Disease And Alcohol Use Disorder

Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction

54712 Bipolar disorder among patients with atopic dermatitis: A case-control study in the All of Us research program

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

Towards precision medicine for anxiety disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration

Obsessive–compulsive disorder among patients with atopic dermatitis: a case–control study in the All of Us research program

Loneliness and depression: bidirectional mendelian randomization analyses using data from three large genome-wide association studies

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

Exploring the genetic overlap between twelve psychiatric disorders

Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology

Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells

Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder

Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records

Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol’s effects

Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses

Collaborators (43)

Cathryn Lewis

Marco Galimberti

Sophie Lehnerer

Christiaan de Leeuw

Joseph Deak

Gerome Breen

Christopher ODonnell

Andrew McIntosh

Per Qvist

Rachel Kember

Aliza Wingo

Thomas D. Als

Ditte Demontis

John McGrath

Fabian Streit

Colin Palmer

Emma C. Johnson

Erkki Isometsä

Philip Jansen

Iiris Hovatta

Anders Rosengren

Henry Kranzler

Thomas E. Nichols

stephan ripke

Maike Stein

Aarno Palotie

Murray Stein

Yousef Khan

Miguel E. Rentería

Sophie van der Sluis

Joel Gelernter

Hyeokmoon Kweon

Michael Benros

Esben Agerbo

Martin Preisig

Josefin Werme

Frank Wendt

Robert Free

Sundararajan Srinivasan

Bernd Taschler

Donald J MacIntyre

Johan Zvrskovec

Max Lam

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