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Giel van Dooren

Senior Lecturer

Australian National University

Australia

Research Interests

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Professors in Australia Professors in Biochemistry Biochemistry professors in Australia

About

Giel van Dooren is a Senior Lecturer at the Australian National University, Australia. His research focuses on the molecular mechanisms of nutrient acquisition and mitochondrial function in intracellular parasitic protists, particularly in the context of malaria. Recent articles explore topics such as antimalarial drug development, lipid dynamics in Plasmodium falciparum, and the characterization of essential proteins in Toxoplasma parasites.

Articles (22)

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Collaborators (21)

Alyssa Ingmundson

GERMANY

Giel van Dooren

Research Interests

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Articles (22)

Nutrient acquisition by intracellular parasitic protists

Inner-mitochondrial membrane protein PfMPV17 is linked to P. falciparum in vitro resistance to the indoloquinolizidine alkaloid alstonine

A novel targeting domain directs essential components of the cytosolic iron–sulfur cluster assembly pathway to the mitochondrion of Toxoplasma parasites

Lipid Droplets, Key Players in the Development of the Malaria Parasite Plasmodium falciparum

Harnessing cholesterol uptake of malaria parasites for therapeutic applications

Lipid droplet dynamics are essential for the development of the malaria parasite Plasmodium falciparum

Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b

A myzozoan-specific protein is an essential membrane-anchoring component of the succinate dehydrogenase complex in Toxoplasma parasites

A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites

Analysis of <i>Plasmodium falciparum</i> Mitochondrial Electron Transport Chain Activity Using Seahorse XFe96 Extracellular Flux Assays.

Analysis of Plasmodium falciparum Mitochondrial Electron Transport Chain Activity Using Seahorse XFe96 Extracellular Flux Assays

An essential role for an Fe-S cluster protein in the cytochrome c oxidase complex of Toxoplasma parasites.

The mystery of massive mitochondrial complexes: the apicomplexan respiratory chain

Real-Time Analysis of Mitochondrial Electron Transport Chain Function in <i>Toxoplasma gondii</i> Parasites Using a Seahorse XFe96 Extracellular Flux Analyzer.

A novel heteromeric pantothenate kinase complex in apicomplexan parasites

Identifying the major lactate transporter of Toxoplasma gondii tachyzoites

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

Control of human toxoplasmosis

Nanos gigantium humeris insidentes: old papers informing new research into Toxoplasma gondii

Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii

A key cytosolic iron–sulfur cluster synthesis protein localizes to the mitochondrion of Toxoplasma gondii

Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites

Collaborators (21)

Alyssa Ingmundson

Kiaran Kirk

Malcolm McConville

Kevin Saliba

Diego Huet

Alexander Maier

Malcolm D. McLeod

Christina Spry

Tina Skinner-Adams

Michael Delves

Tania de Koning-Ward

Nicholas Smith

Erick Tjhin

Brad Sleebs

Jacinta Macdonald

Adele Lehane

Kiran Javed

Lilach Sheiner

Kai Matuschewski

Stefan Broer

Elizabeth Winzeler

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