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Michael Delves

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London School of Hygiene & Tropical Medicine

United Kingdom

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Recent Grants

Grant: Close

Exploring how energy metabolism differs in male and female Plasmodium falciparum gametocytes

Open Date: 2019-09-22

Close Date: 2023-03-30

Grant: Close

Preventing the transmission of artemisinin resistant falciparum malaria

Open Date: 2016-01-01

Close Date: 2017-12-31

Articles (20)

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Collaborators (15)

Colin Sutherland

Professor of Parasitology

London School of Hygiene and Tropical Medicine Faculty of Infectious and Tropical Diseases

UNITED KINGDOM

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Lyn-Marie Birkholtz

Professor and Research Chair

Stellenbosch University

SOUTH AFRICA

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Muhammed Afolabi

Clinical Associate Professor & UKRI Future Leaders Fellow

London School of Hygiene & Tropical Medicine

UNITED KINGDOM

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Tania de Koning-Ward

Professor of Molecular Microbiology

Deakin University

AUSTRALIA

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Marcus Lee

Professor

University of Dundee

UNITED KINGDOM

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Lazaros Papageorgiou

University College London

UNITED KINGDOM

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Brad Sleebs

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Wai-Hong Tham

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Jake Baum

Professor of Infectious Diseases

University of New South Wales

AUSTRALIA

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Adele Lehane

Australian National University

AUSTRALIA

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Giel van Dooren

Senior Lecturer

Australian National University

AUSTRALIA

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Beatriz Baragaña

Academic, Principal Investigator/Senior Lecturer (Teaching and Research)

University of Dundee

UNITED KINGDOM

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Nicholas Furnham

Associate Professor

London School of Hygiene & Tropical Medicine

UNITED KINGDOM

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Alyssa Barry

Professor

Deakin University

AUSTRALIA

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Elizabeth Winzeler

Professor

University of California, San Diego

UNITED STATES

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Michael Delves

Research Interests

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Recent Grants

Articles (20)

Structure guided optimization of novel inhibitors of Plasmodium lysyl-tRNA synthetase with multistage activity against malaria parasites

Prioritising in a crisis: what next for malaria research?

The translatome of quiescent Plasmodium falciparum gametocytes reveals parasite pyridoxal 5'-phosphate (PLP) biosynthesis is essential for efficient mosquito stage development.

Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase.

Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4.

Characterizing the quick-killing mechanism of action of azithromycin analogs against malaria parasites

Optimization and Characterization of the Antimalarial Activity of N-Aryl Acetamides that are Susceptible to Mutations in ROM8 and CSC1

Targeting Aurora Kinases as Essential Cell-Cycle Regulators to Deliver Multi-Stage Antimalarials Against Plasmodium Falciparum

Correction: Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.

Optimisation-based modelling for explainable lead discovery in malaria

Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.

Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b

Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.

Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4.

A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo

Mitochondrial ATP synthesis is essential for efficient gametogenesis in Plasmodium falciparum

Tambjamines as Fast-Acting Multistage Antimalarials.

Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.

A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations.

Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.

Collaborators (15)

Colin Sutherland

Lyn-Marie Birkholtz

Muhammed Afolabi

Tania de Koning-Ward

Marcus Lee

Lazaros Papageorgiou

Brad Sleebs

Wai-Hong Tham

Jake Baum

Adele Lehane

Giel van Dooren

Beatriz Baragaña

Nicholas Furnham

Alyssa Barry

Elizabeth Winzeler

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