John Scott

Has grant

Lab Head, Neurometabolism

Monash Institute of Pharmaceutical Sciences

Australia

Research Interests

Explore related searches

Professors in Australia

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

John Scott is a Lab Head specializing in Neurometabolism at the Monash Institute of Pharmaceutical Sciences in Australia. His research focuses on the roles of calcium signaling and energy metabolism, as evidenced by his recent publications investigating the unconventional binding of Calmodulin to kinases, the effects of CAMKK2 on obesity, and mechanisms underlying AMPK signaling. His work also explores the intersection of metabolic regulation and neurological factors, contributing to pathways associated with autism.

Recent Grants

Grant: Close

Uncovering New Mechanisms of Metabolite-Sensing and Signaling

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Validating CaMKK2 as a Rational Treatment Target for Bipolar Disorder

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Regulation of energy metabolism by CaMKK2

Open Date: 2018-01-01

Close Date: 2020-12-31

Grant: Close

Signaling pathways to enhance potency of AMPK-targeting drugs

Open Date: 2016-01-01

Close Date: 2018-01-01

Grant: Close

Metabolic stress sensing by AMPK: implications for energy balance and isoform-targetting therapeutics

Open Date: 2013-01-01

Close Date: 2015-01-01

Articles (19)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Collaborators (24)

Daniel Singh

Head Tutor

University of Queensland

AUSTRALIA

John Scott

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (19)

Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity

Myeloid-specific CAMKK2 deficiency protects against diet-induced obesity and insulin resistance by rewiring metabolic gene expression and enhancing energy expenditure.

Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827.

Comparison of Classical P81 and SVI-P Cation-Exchange Papers in Radiometric Protein Kinase Assays.

AMPK phosphosite profiling by label-free mass spectrometry reveals a multitude of mTORC1-regulated substrates

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins.

Sensing of Long-Chain Fatty Acyl-CoA Esters by AMPK.

Extracellular vesicles contribute to the beneficial effects of exercise training in APP/PS1 mice

CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing

Large Scale Genomic Investigation of Pediatric Cholestasis Reveals a Novel Hepatorenal Ciliopathy Caused by PSKH1 Mutations

Convergence on CaMK4: a key modulator of autism-associated signaling pathways in neurons

SGC-CAMKK2-1: A Chemical Probe for CAMKK2

CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

Exercise training improves long-term memory in obese mice

Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals

CaMKK2 as an emerging treatment target for bipolar disorder.

Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Collaborators (24)

Daniel Singh

Janni Petersen

Olga Göransson

David H. Drewry

Daniel Frigo

Opher Gileadi

Laura Dagley

Kei Sakamoto

Danial Ahwazi

Atul Deshmukh

Jianhan Wu

Jeffrey Brault

Robyn M. Murphy

Bradley S. Launikonis

Christopher Lewis

Mark A Febbraio

James Murphy

Julien Ochala

Jae Pyun

Alex Addinsall

Carrow Wells

Conchita Fraguas Bringas

Jon Oakhill

Sandra Galic

Make your next move.