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Kathrin Bernt

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Children's Hospital of Philadelphia

United States

Research Interests

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Recent Grants

Grant: Close

Venetoclax for infant ALL – COG AALL2321

Open Date: 2024-05-01

Close Date: 2026-04-30

Grant: Open

IDP mediated transcriptional stabilization as a cause of AML

Open Date: 2022-04-01

Close Date: 2027-03-31

Grant: Open

A stalled chromatin regulatory network that mediates the oncogenic activity of Meningioma-1

Open Date: 2022-04-01

Close Date: 2027-03-31

Grant: Close

Center for Developmental Mapping of Heart and Bone Tissues

Open Date: 2020-09-01

Close Date: 2022-08-31

Grant: Close

A Multi-Omics Approach to Overcome Resistance in Infant Leukemia by Identifying Immune Therapy Failure Mechanisms

Open Date: 2020-07-01

Close Date: 2024-06-30

Articles (17)

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2023

Collaborators (12)

Hua Huang

University of Pennsylvania

UNITED STATES

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Mignon L. Loh

Professor

University of Washington

UNITED STATES

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Assistant Professor of Pediatrics

University of Washington

UNITED STATES

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ApplyKite TwinLearns as you apply

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Kathrin Bernt

Research Interests

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Recent Grants

Articles (17)

Plasticity under pressure: biology and detection of lineage switch in acute leukemia.

Whack-a-menin: zifto’s preclinical activity and mutant MEN1

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.

Single-nucleus multiomic analysis of Beckwith-Wiedemann syndrome liver reveals PPARA signaling enrichment and metabolic dysfunction

Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists.

Hodgkin Lymphoma Diagnosed by Endobronchial Ultrasound Guided Cryobiopsy, a Minimally Invasive Diagnostic Technique

Identification and characterization of chemotherapy resistant high-risk neuroblastoma persister cells

A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia.

The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.

CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma.

FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia

Mapping human hematopoiesis

Menin dependence: UBTF-ITD AML joins the club

Rethinking paraneoplastic eosinophilia

The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis

Collaborators (12)

Hua Huang

Mignon L. Loh

P Jeremy Wang

Alexandra Kovach

Jason Kurzer

Thierry BESSON

Kristopher Bosse

Kai Tan

Adam Wolpaw

Gang Wu

Pamela Sung

Lauren Grant

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