M. Amelia Santos

Professor

Universidade de Lisboa Instituto Superior Técnico

Portugal

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Professor M. Amelia Santos is a faculty member at Universidade Técnica de Lisboa Instituto Superior Técnico, Portugal. Her research focuses on medicinal chemistry and neurodegenerative diseases, with recent publications addressing drug development strategies for Alzheimer’s disease and innovative imaging probes. She has contributed to advancing the understanding of metal-modulating compounds and their therapeutic potential in treating complex neurological conditions.

M. Amelia Santos

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Articles (22)

Rivastigmine Templates with Antioxidant Motifs—A Medicinal Chemist’s Toolbox Towards New Multipotent AD Drugs

Gadolinium Complex with Tris-Hydroxypyridinone as an Input for New Imaging Probes: Thermodynamic Stability, Molecular Modeling and Biodistribution

Editorial on Special Issue “The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs”

Exploiting the potential of rivastigmine-melatonin derivatives as multitarget metal-modulating drugs for neurodegenerative diseases

Solution studies, synthesis and antibacterial activity of Ga(III) complexes with bis-kojate derivatives

New Multitarget Rivastigmine–Indole Hybrids as Potential Drug Candidates for Alzheimer’s Disease

Solution chemistry of oxidovanadium(IV) complexes with two bis-kojic acid derivatives

Rivastigmine–Benzimidazole Hybrids as Promising Multitarget Metal-Modulating Compounds for Potential Treatment of Neurodegenerative Diseases

Rivastigmine-Benzimidazole Hybrids as Promising Multitarget Metal-Modulating Compounds for Potential Treatment of Neurodegenerative Diseases

A novel organic semiconductor 4-phenylthiazol-2-yl-(phenylhydrazono) acetonitrile (PTPA) thin films: synthesis, optical and electrical properties

Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease

Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer’s Disease

Hydroxypyridinone-Based Metal Chelators towards Ecotoxicity: Remediation and Biological Mechanisms

GdIII and GaIII complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution

A Multi-Technique Investigation of the Complex Formation Equilibria between Bis-Deferiprone Derivatives and Oxidovanadium (IV)

Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer's Disease

Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease

Hydroxypyridinone-Based Metal Chelators towards Ecotoxicity: Remediation and Biological Mechanisms

Multifunctional Small Molecules as Potential Anti-Alzheimer’s Disease Agents

Recent Multi-target Approaches on the Development of Anti- Alzheimer's Agents Integrating Metal Chelation Activity

Novel Donepezil–Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer’s Disease

Bifunctional 3-Hydroxy-4-Pyridinones as Potential Selective Iron(III) Chelators: Solution Studies and Comparison with Other Metals of Biological and Environmental Relevance

Collaborators (19)

Giuseppe Sciortino

Antonio Laghezza

M. EUGENIA DE LEON GONZALEZ

Valeria Marina Nurchi

Sandra M Cardoso

Sílvia Chaves

Rita C. Guedes

Péter Buglyó

Francesco Crea

David Vicente-Zurdo

Concetta De Stefano

Alessia Carocci

Lurdes Gano

Darren M. Griffith

Luca Piemontese

Éva Tóth

Cosimo Altomare

Eugenio Garribba

Katalin Várnagy

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