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Paul G Thomas

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Professor

Fred Hutch Cancer Center

United States

Research Interests

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Recent Grants

Grant: Close

DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSES

Open Date: 2020-06-29

Close Date: 2025-05-31

Grant: Close

DIVINCI: Dissection of Influenza Vaccination and Infection for Childhood Immunity

Open Date: 2019-05-02

Close Date: 2026-04-30

Grant: Close

Decoding the interactions between T cell receptors and peptide-MHC

Open Date: 2018-06-20

Close Date: 2023-05-31

Grant: Close

A protective role for gamma delta T cells in respiratory infection

Open Date: 2016-03-01

Close Date: 2021-02-28

Articles (20)

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Collaborators (31)

My Ha

Senior Researcher

University of Antwerp

BELGIUM

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Ye Shen

UNITED STATES

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Aisha Souquette

Research Associate Professor

University of Maryland

UNITED STATES

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Q. Sue Huang

Institute of Environmental Sciences and Research

NEW ZEALAND

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Christopher Lazarski

Assistant Professor

George Washington University

UNITED STATES

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Nicole La Gruta

Department Head

MONASH UNIVERSITY

AUSTRALIA

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Hanne Vibeke Hansen Marquart

Chief Physician; MD, PhD, Clinical Associate Professor

Copenhagen University Hospital

DENMARK

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Anastasia Minervina

Staff Scientist

Fred Hutch Cancer Center

UNITED STATES

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THI HOANG OANH NGUYEN

University of Melbourne

AUSTRALIA

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Gregory Cuny

University of Houston

UNITED STATES

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Wangnan Cao

Assisstant Professor

Peking University

CHINA

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Carolien van de Sandt

Team Leader/Senior Research Fellow

Murdoch Childrens Research Institute

AUSTRALIA

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Heather Sheppard

Associate Professor

Arkansas State University

UNITED STATES

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Stijn Vanhee

Assistent Professor

Ghent University

BELGIUM

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Jason Tye-Din

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Mark Hatley

Associate Member

St. Jude Children's Research Hospital

UNITED STATES

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Michael Keller

Assistant Professor

George Washington University

UNITED STATES

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Shanmuganathan Chandrakasan

Emory University School of Medicine

UNITED STATES

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John Choi

The University of Alabama

UNITED STATES

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Hayley McQuilten

Peter Doherty Institute

AUSTRALIA

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Rebekah Honce

Assistant Professor

University of Vermont

UNITED STATES

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Mark Brimble

Assistant Professor

University of Washington Medical Center

UNITED STATES

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Justin Bahl

University of Georgia

UNITED STATES

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Beisi Xu

Principal Bioinformatics Research Scientist

St. Jude Children's Research Hospital

UNITED STATES

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Andreas Handel

Professor

University of Georgia

UNITED STATES

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Diego Rodriguez

Group Leader

University of Bonn

GERMANY

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Benson Ogunjimi

Assistant Professor

University of Antwerp

BELGIUM

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Pirooz Zareie

MONASH UNIVERSITY

AUSTRALIA

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Jamie Rossjohn

MONASH UNIVERSITY

AUSTRALIA

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Aleksandra M. Walczak

FRANCE

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Rishi Kotecha

Laboratory Head

Telethon Kids Institute

AUSTRALIA

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Paul G Thomas

Research Interests

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Recent Grants

Articles (20)

Uneven TCR chain pairing constraints govern epitope recognition

Gliadin-Specific CD4⁺ T Cells Exhibit Functional Diversity Independent of TCR Usage or Epitope Specificity

Entering the Age of Specificity in T Cell Immunity

High-Dose Inactivated Influenza Vaccine Inconsistently Improves Heterologous Antibody Responses in an Older Human Cohort

Central memory T cells with key TCR repertoires and gene expression profiles dominate influenza CD8+ T cell pools across the human lifespan

T cell receptor specificity landscape revealed through de novo peptide design

Memories are I(F)N-credibly protective

Biologic and clinical analysis of childhood gamma delta T-ALL identifies LMO2/STAG2 rearrangements as extremely high-risk.

Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication

Impact of the COVID‐19 related border restrictions on influenza and other common respiratory viral infections in New Zealand

Necroptosis blockade prevents lung injury in severe influenza.

Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation

Pre-Existing Immunity to a Nucleic Acid Contaminant-Derived Antigen Mediates Transaminitis and Resultant Diminished Transgene Expression in a Mouse Model of Hepatic Recombinant Adeno-Associated Virus-Mediated Gene Transfer

Diet-induced obesity affects influenza disease severity and transmission dynamics in ferrets

Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice

Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma

Immune Cell Profiles of Patients with Sickle Cell Disease during Parvovirus B19–Induced Transient Red Cell Aplasia

Lack of memory recall in human CD4 T cells elicited by the first encounter with SARS-CoV-2.

Principles and therapeutic applications of adaptive immunity.

Collaborators (31)

My Ha

Ye Shen

Aisha Souquette

Q. Sue Huang

Christopher Lazarski

Nicole La Gruta

Hanne Vibeke Hansen Marquart

Anastasia Minervina

THI HOANG OANH NGUYEN

Gregory Cuny

Wangnan Cao

Carolien van de Sandt

Heather Sheppard

Stijn Vanhee

Jason Tye-Din

Mark Hatley

Michael Keller

Shanmuganathan Chandrakasan

John Choi

Hayley McQuilten

Rebekah Honce

Mark Brimble

Justin Bahl

Beisi Xu

Andreas Handel

Diego Rodriguez

Benson Ogunjimi

Pirooz Zareie

Jamie Rossjohn

Aleksandra M. Walczak

Rishi Kotecha

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