Wolf-Dietrich Hardt

Professor of Microbiology

Eidgenössische Technische Hochschule Zürich

Switzerland

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Professor Wolf-Dietrich Hardt is a faculty member in the Department of Microbiology at Eidgenössische Technische Hochschule Zürich, Switzerland. His research focuses on the interactions between the gut microbiota and enteric pathogens, particularly in the context of Salmonella and its virulence mechanisms. Recent publications include studies on carbohydrate metabolism in Enterobacteriaceae and the role of commensal E. coli in mediating Salmonella colonization and elimination in the gut.

Wolf-Dietrich Hardt

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Articles (20)

Gene-level analysis of core carbohydrate metabolism across the Enterobacteriaceae pan-genome

Neutrophil recruitment during intestinal inflammation primes Salmonella elimination by commensal E. coli in a context-dependent manner.

Monosaccharides drive Salmonella gut colonization in a context-dependent or -independent manner.

Metabolic network reconstruction as a resource for analyzing Salmonella Typhimurium SL1344 growth in the mouse intestine

Strain-specific galactose utilization by commensal E. coli mitigates Salmonella establishment in the gut

Context-dependent change in the fitness effect of (in)organic phosphate antiporter glpT during Salmonella Typhimurium infection

Comparing <i>Campylobacter jejuni</i> to three other enteric pathogens in OligoMM <sup>12</sup> mice reveals pathogen-specific host and microbiota responses

Antibiotic-recalcitrant Salmonella exploits post-antibiotic microbiota disruption to achieve virulence-dependent transmission

Mechanisms conferring multi-layered protection against intestinal Salmonella Typhimurium infection

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut

Studying antibiotic persistence in vivo using the model organism Salmonella Typhimurium

A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface

Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium

CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis

Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire

Microbiota-derived metabolites inhibit Salmonella virulent subpopulation development by acting on single-cell behaviors

Elucidating host–microbe interactions in vivo by studying population dynamics using neutral genetic tags

Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo

Evolutionary causes and consequences of bacterial antibiotic persistence

Collaborators (11)

Annika Hausmann

Vassily Hatzimanikatis

Mikael Sellin

Erik Bakkeren

Evangelia Vayena

Christian von Mering

Yassine Cherrak

Alyson Hockenberry

Maria Letizia Di Martino

Jens Eriksson

Steffen Boettcher

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